3’-O-(t-Butyldiphenylsilyl) thymidine

Modify Date: 2025-09-18 09:54:21

3’-O-(t-Butyldiphenylsilyl) thymidine structure	Common Name	3’-O-(t-Butyldiphenylsilyl) thymidine
	CAS Number	83467-48-5	Molecular Weight	320.10
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₃DTBN₂O₅PS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3’-O-(t-Butyldiphenylsilyl) thymidine

3’-O-(t-Butyldiphenylsilyl) thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Deoxy-3'-O-[(2-methyl-2-propanyl)(diphenyl)silyl]-3,4-dihydrot hymidine
Synonym	More Synonyms

Description	3’-O-(t-Butyldiphenylsilyl) thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₀H₁₃DTBN₂O₅PS
Molecular Weight	320.10
Exact Mass	480.20800
PSA	93.81000
LogP	2.48230

Precursor 8
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