5'-O-Dimethoxytrityl-deoxythymidine structure
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Common Name | 5'-O-Dimethoxytrityl-deoxythymidine | ||
|---|---|---|---|---|
| CAS Number | 40615-39-2 | Molecular Weight | 528.596 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C31H32N2O7 | Melting Point | 114-116 °C (subl.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of 5'-O-Dimethoxytrityl-deoxythymidine5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides[1]. |
| Name | 5'-O-(4,4'-Dimethoxytrityl)thymidine |
|---|---|
| Synonym | More Synonyms |
| Description | 5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides[1]. |
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| Related Catalog | |
| References |
[1]. Lars Holmberg. Method and means for oligonucleotide synthesis. WO1992009615A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Melting Point | 114-116 °C (subl.)(lit.) |
| Molecular Formula | C31H32N2O7 |
| Molecular Weight | 528.596 |
| Exact Mass | 528.226013 |
| PSA | 112.01000 |
| LogP | 6.97 |
| Index of Refraction | 1.596 |
| Storage condition | −20°C |
| Stability | Store in Freezer |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Precursor 10 | |
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| DownStream 10 | |
| HS Code | 29349990 |
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Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.
Nucleic Acids Res. 8(22) , 5473-89, (1980) Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially availabl... |
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Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.
Nucleic Acids Res. 10(10) , 3291-301, (1982) A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleosi... |
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Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.
Bioorg. Med. Chem. Lett. 8(9) , 1123-6, (1998) A novel solid-phase synthesis of 5'-radiolabeled oligonucleotides is described. The labeling reaction is carried out by the phosphoramidite method with the aid of [4,6-di-14C]-5'-dimethoxytritylthymid... |
| Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- |
| 5'-O-dimethyltritylthymidine |
| 5'-O-(Bis(4-methoxyphenyl)phenylmethyl)thymidine |
| EINECS 255-003-1 |
| 2,4(1H,3H)-pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-glycero-pentofuranosyl]-5-methyl- |
| 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5S)-tetrahydro-5-[1-methoxy-1-(methyldioxy)-2,2,2-triphenylethyl]-2-furanyl]- |
| 1-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-β-D-glycero-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione |
| MFCD00010113 |
| 5′-O-(4,4′-Dimethoxytrityl)thymidine |
| 5'-O-Dimethoxytrityl-deoxythymidine |
| 1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| DMTr-dThd |
| 5‘-O-Dimethoxytrityl-deoxythymidine |
| 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]thymidine |
| 1-{(2R,5S)-5-[1-Methoxy-1-(methylperoxy)-2,2,2-triphenylethyl]tetrahydro-2-furanyl}-5-methyl-2,4(1H,3H)-pyrimidinedione |