Regorafenib N-Oxide(M2)

Modify Date: 2025-08-27 09:31:04

Regorafenib N-Oxide(M2) structure	Common Name	Regorafenib N-Oxide(M2)
	CAS Number	835621-11-9	Molecular Weight	498.81500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₅ClF₄N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Regorafenib N-Oxide(M2)

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

Name	bay 75-7495
Synonym	More Synonyms

Description	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
References	[1]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48.

Molecular Formula	C₂₁H₁₅ClF₄N₄O₄
Molecular Weight	498.81500
Exact Mass	498.07200
PSA	104.92000
LogP	6.25920

Regorafenib N-oxide (M2 Metabolite)

Regorafenib N-Oxide(M2)

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Regorafenib N-Oxide(M2)

Use of Regorafenib N-Oxide(M2)

Names

Regorafenib N-Oxide(M2) Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.