1,4-DIACETOXY-2,3-DICYANOBENZENE

Modify Date: 2024-01-11 19:27:20

1,4-DIACETOXY-2,3-DICYANOBENZENE Structure
1,4-DIACETOXY-2,3-DICYANOBENZENE structure
Common Name 1,4-DIACETOXY-2,3-DICYANOBENZENE
CAS Number 83619-73-2 Molecular Weight 244.20300
Density 1.34g/cm3 Boiling Point 447.5ºC at 760 mmHg
Molecular Formula C12H8N2O4 Melting Point 166-167ºC(lit.)
MSDS USA Flash Point 195.2ºC

 Use of 1,4-DIACETOXY-2,3-DICYANOBENZENE


1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH[1].

 Names

Name (4-acetyloxy-2,3-dicyanophenyl) acetate
Synonym More Synonyms

 1,4-DIACETOXY-2,3-DICYANOBENZENE Biological Activity

Description 1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH[1].
Related Catalog
References

[1]. Cook JA, et, al. Intracellular pH measurements using flow cytometry with 1,4-diacetoxy-2,3-dicyanobenzene. Cytometry. 1988 Sep;9(5):441-7.

 Chemical & Physical Properties

Density 1.34g/cm3
Boiling Point 447.5ºC at 760 mmHg
Melting Point 166-167ºC(lit.)
Molecular Formula C12H8N2O4
Molecular Weight 244.20300
Flash Point 195.2ºC
Exact Mass 244.04800
PSA 100.18000
LogP 1.28056
Index of Refraction 1.553

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2926909090

 Synthetic Route

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1,4-DIACETOXY-2,3-DICYANOBENZENE Structure

1,4-DIACETOXY-2...

CAS#:83619-73-2

Literature: Thiele; Guenther Justus Liebigs Annalen der Chemie, 1906 , vol. 349, p. 64

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1,4-DIACETOXY-2,3-DICYANOBENZENE Structure

1,4-DIACETOXY-2...

CAS#:83619-73-2

Literature: Thiele; Guenther Justus Liebigs Annalen der Chemie, 1906 , vol. 349, p. 64

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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 Synonyms

Benzene,1,4-diacetyloxy-2,3-dicyano
1,4-Diacetoxy-2,3-dicyanobenzene
DADCB
D0679_SIAL
3,6-Diacetoxyphthalonitrile
3.6-Diacetoxy-phthalsaeure-dinitril
2,3-Dicyanochinol-diacetat
2,3-Dicyano-1,4-hydroquinone diacetate