Salvinorin A(Divinorin A)
Salvinorin A(Divinorin A) structure
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Common Name | Salvinorin A(Divinorin A) | ||
|---|---|---|---|---|
| CAS Number | 83729-01-5 | Molecular Weight | 432.464 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 563.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C23H28O8 | Melting Point | 238-240ºC | |
| MSDS | USA | Flash Point | 294.8±30.1 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
Use of Salvinorin A(Divinorin A)Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway. Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage. |
| Name | methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.8±50.0 °C at 760 mmHg |
| Melting Point | 238-240ºC |
| Molecular Formula | C23H28O8 |
| Molecular Weight | 432.464 |
| Flash Point | 294.8±30.1 °C |
| Exact Mass | 432.178406 |
| PSA | 109.11000 |
| LogP | 1.82 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.548 |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302 + H312 + H332-H319 |
| Precautionary Statements | P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | F,Xn |
| Risk Phrases | 11-20/21/22-36 |
| Safety Phrases | S22-S24/25 |
| RIDADR | UN 1648 3 / PGII |
| RTECS | QL6127142 |
![(2S,6aS,7R,9S,10aS,10bR)-9-((benzyloxy)methoxy)-7-(dimethoxymethyl)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-1,4,6,6a,7,8,9,10,10a,10b-decahydro-2H-benzo[f]isochromen-5-yl trifluoromethanesulfonate structure](https://image.chemsrc.com/caspic/469/947596-83-0.png)
![(2S,4aR,6aR,7R,9S,10R,10aS,10bR)-9,10-(dihydroxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4-oxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester structure](https://image.chemsrc.com/caspic/290/92545-29-4.png)
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Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.
J. Pharmacol. Exp. Ther. 350(1) , 69-78, (2014) The opioid and cannabinoid systems play a crucial role in multiple physiological processes in the central nervous system and in the periphery. Selective opioid as well as cannabinoid (CB) receptor ago... |
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Regulating a novel drug: an evaluation of changes in use of Salvia divinorum in the first year of Florida's ban.
Int. J. Drug Policy 23(6) , 512-21, (2012) A plant with dissociative and psychoactive properties began to attract the attention of the media and United States policymakers following a well-publicized suicide in 2006 and reports that the plant ... |
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Development of an enzyme immunoassay using a monoclonal antibody against the psychoactive diterpenoid salvinorin A.
J. Nat. Prod. 76(9) , 1654-60, (2013) Salvinorin A (1), the main active constituent in Salvia divinorum, is a highly selective kappa-opioid receptor agonist with hallucinogenic effects, which is regulated in several countries. In the pres... |
| Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate |
| 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)- |
| methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate |
| Divinorin A |
| salvonorin A |
| 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,7R,9S,10aS,10bR)- |
| Salvinorin |
| Methyl (2S,4aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate |
| Salvinorin A |
| MFCD05664742 |
| Diviner's Sage |
| Mexican mint |
| herbal ecstasy |