Deschloro Cetirizine Dihydrochloride

Modify Date: 2024-01-07 11:40:48

Deschloro Cetirizine Dihydrochloride Structure
Deschloro Cetirizine Dihydrochloride structure
Common Name Deschloro Cetirizine Dihydrochloride
CAS Number 83881-54-3 Molecular Weight 427.36500
Density N/A Boiling Point 515.6ºC at 760 mmHg
Molecular Formula C21H28Cl2N2O3 Melting Point N/A
MSDS N/A Flash Point 265.6ºC

 Use of Deschloro Cetirizine Dihydrochloride


Deschloro Cetirizine Dihydrochloride is a Cetirizine impurity. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.

 Names

Name {2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy}acetic acid dihydroch loride

 Deschloro Cetirizine Dihydrochloride Biological Activity

Description Deschloro Cetirizine Dihydrochloride is a Cetirizine impurity. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.
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 Chemical & Physical Properties

Boiling Point 515.6ºC at 760 mmHg
Molecular Formula C21H28Cl2N2O3
Molecular Weight 427.36500
Flash Point 265.6ºC
Exact Mass 426.14800
PSA 53.01000
LogP 3.97460
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AH3193666
CHEMICAL NAME :
Acetic acid, (2-(2-(4-(diphenylmethyl)-1-piperazinyl)ethoxy)ethoxy )-, dihydrochloride
CAS REGISTRY NUMBER :
83881-54-3
LAST UPDATED :
199606
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H30-N2-O4.2Cl-H
MOLECULAR WEIGHT :
471.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
942 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4525358
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