Hydroxy-alpha-sanshool

Modify Date: 2024-01-20 16:13:45

Hydroxy-alpha-sanshool Structure
Hydroxy-alpha-sanshool structure
Common Name Hydroxy-alpha-sanshool
CAS Number 83883-10-7 Molecular Weight 263.37500
Density 0.973 g/cm3 Boiling Point 471.5±45.0℃ at 760 mmHg
Molecular Formula C16H25NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-alpha-sanshool


Hydroxy-​α-​sanshool is an alkylamide isolated from pepper, acts as a TRPA1 covalent and TRPV1 non-covalent agonist, with EC50s of 69 and 1.1 µM, respectively[1].

 Names

Name alpha-Hydroxy-Sanshool
Synonym More Synonyms

 Hydroxy-alpha-sanshool Biological Activity

Description Hydroxy-​α-​sanshool is an alkylamide isolated from pepper, acts as a TRPA1 covalent and TRPV1 non-covalent agonist, with EC50s of 69 and 1.1 µM, respectively[1].
Related Catalog
Target

EC50: 69 µM (TRPA1), 1.1 µM (TRPV1)[1]

References

[1]. Koo JY, et al. Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol. 2009 Aug;157(8):1398-409.

 Chemical & Physical Properties

Density 0.973 g/cm3
Boiling Point 471.5±45.0℃ at 760 mmHg
Molecular Formula C16H25NO2
Molecular Weight 263.37500
Exact Mass 263.18900
PSA 49.33000
LogP 3.28930
Storage condition 2-8℃

 Safety Information

HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

(2E,6Z,8E,10E)-N-(2-HYDROXY-2-METHYL-PROPYL)DODECA-2,6,8,10-TETRAENAMIDE
(2E,6Z,8E,10E)-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide