Flavin adenine dinucleotide disodium salt

Modify Date: 2025-08-22 10:07:30

Flavin adenine dinucleotide disodium salt Structure
Flavin adenine dinucleotide disodium salt structure
Common Name Flavin adenine dinucleotide disodium salt
CAS Number 84366-81-4 Molecular Weight 829.51
Density N/A Boiling Point N/A
Molecular Formula C27H31N9Na2O15P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Flavin adenine dinucleotide disodium salt


Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

 Names

Name Flavin adenine dinucleotide disodium salt
Synonym More Synonyms

  Biological Activity

Description Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
Related Catalog
In Vitro Poly(Flavin Adenine Dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry[2].
In Vivo With flavin adenine dinucleotide (2 mg/kg), the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT) is significantly cancelled. Flavin Adenine Dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin Adenine Dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin Adenine Dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine[1].
References

[1]. Sugiyama S, et al. Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. Jpn Heart J. 1979 Sep;20(5):657-65.

[2]. Karyakin AA, et al. Electropolymerized flavin adenine dinucleotide as an advanced NADH transducer. Anal Chem. 2004 Apr 1;76(7):2004-9.

 Chemical & Physical Properties

Molecular Formula C27H31N9Na2O15P2
Molecular Weight 829.51
PSA 397.44000
InChIKey XLRHXNIVIZZOON-WFUPGROFSA-L
SMILES Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC(O)C(O)C(O)COP(=O)([O-])OP(=O)([O-])OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)c2cc1C.[Na+].[Na+]
Storage condition 2-8°C
Water Solubility 5 g/L

 Safety Information

Hazard Codes Xi
Safety Phrases S24/25-S22
WGK Germany 3

 Bioassay

View more

Name: qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa...
Source: 824
Target: AR protein [Homo sapiens]
External Id: MDAN535
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel...
Source: 824
Target: RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein
External Id: ELG271
Name: qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
Source: 824
Target: thyroid hormone receptor beta isoform 2 [Rattus norvegicus]
External Id: TRN186
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
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 Synonyms

Flavaspidic acid
Polystichocitrin
MFCD00151217
5'->5'-ester with adenosine,disodium salt
Toxifren
Glavaspidic acid
Flavaspidsaeure
flavaspidic acid AB
EINECS 282-733-8
Flavaspidic acid BB
flavin-adenin dinucleotide,disodium salt
flaspidic acid-BBBB
flavine-adenine-dinucleotide disodium-salt
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