AP102

Modify Date: 2024-01-12 16:55:53

AP102 Structure
AP102 structure
 Common Name AP102
CAS Number 846569-60-6 Molecular Weight 1313.07
Density N/A Boiling Point N/A
Molecular Formula C50H66I2N12O10S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AP102


AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research[1].

 Names

Name AP102

 AP102 Biological Activity

Description AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research[1].
Related Catalog
Target

SSTR2:0.63 nM (IC50)

SSTR5:0.65 nM (IC50)

References

[1]. Tarasco E, et al. Effect of AP102, a subtype 2 and 5 specific somatostatin analog, on glucose metabolism in rats. Endocrine. 2017 Oct;58(1):124-133.  

 Chemical & Physical Properties

Molecular Formula C50H66I2N12O10S2
Molecular Weight 1313.07
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Chemsrc provides AP102(CAS#:846569-60-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of AP102 are included as well.>> amp version: AP102

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