Olmesartan lactone impurity

Modify Date: 2024-01-09 18:10:33

Olmesartan lactone impurity structure	Common Name	Olmesartan lactone impurity
	CAS Number	849206-43-5	Molecular Weight	428.48600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₄N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Olmesartan lactone impurity

Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study[1][2].

Name	6,6-dimethyl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]furo[3,4-d]imidazol-4-one

Description	Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor
References	[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7. [2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

Description

Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study[1][2].

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor

References

[1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.

[2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

Molecular Formula	C₂₄H₂₄N₆O₂
Molecular Weight	428.48600
Exact Mass	428.19600
PSA	98.58000
LogP	4.13650

RIDADR	NONH for all modes of transport

DC Chemicals Limited
China
Product Name: Olmesartan lactone impurity
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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