879562-26-2

879562-26-2 structure

Name: Olmesartan medoxomil impurity C
Chemical Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
CAS Number: 879562-26-2
Molecular Formula: C₂₉H₂₈N₆O₅
Molecular Weight: 540.57000
Catalog: Signaling Pathways GPCR/G Protein Angiotensin Receptor
Create Date: 2018-10-10 20:38:36
Modify Date: 2026-07-02 07:30:13
Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.

Name	(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
Synonyms	Olmestan Medoxomil Olefinic Impurity olmesartan medoxomil dehydrate Olmestan Medoxomil Impurity C, RNH-6373 OlMestan MedoxoMil IMpurity C (Dehydro IMpurity) 4-(1-Methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-cboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methylester (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-Methylethenyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-cboxylate 4-(1-Methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl] Olmestan medoxomil impurity Ⅰ Olmestan ester impurity C DES(1-hydroxy-1-methylethyl)-(1-methylethenyl)-olmestan medoxomil Olmestan Impurity 3(Olmestan Medoxomil Impurity C) Anhydro Olmestan Medoxomil Olmestan Medoxomil Impurity D(Olmestan Medoxomil Impurity C) Olmestan imp C Olmestan Medoxomil Impurity C (Dehydro Impurity), RNH-6373 (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-cboxylate (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-Methylethenyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)bipheny Dehydro Olmesartan Medoxomil Olmestan impuirty C 1H-Imidazole-5-cboxylic acid, 4-(1-methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(1H-tetrazol-5-yl) -[1,1'-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidaze -5-cboxylate (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-[[2’-(5-Tetrazolyl)-4-biphenylyl]methyl]-4-(1-propen-2-yl)-2-propylimidazole-5-cboxylate Olmestan Medoxomil impurity 12/Olmestan Medoxomil Impurity C/Dehydro Olmestan Medoxomil/(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2-(2H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-cboxylate (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-cboxylate Olmestan Medoxomil-3 Olmestan Medoxomil Impurity RNH-6270（4-（1-hydroxy-1-methylethyl）-2-propyl-1-[[2’-（1H-tetrazol-5-yl）biphenyl-4-yl]methyl]-1H-imidazole-5-cboxylic acid） Olmestan Medoxomil Dehydro OlMestan MedoxoMil iMpurity I Olmestan Medoxomil Impurity D Olmestan Impurity C/ Olmestan Medoxomil Olefinic Impurity (Dehydro Olmestan Medoxomil/ Anhydro Olmestan Medoxomil) OlMestan IMpurity C (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-cboxylate Azilstan medoxomil impurity239 OlMestan IMp C (Dehydro OlMestanMedoxoMil) (OlMestan Styrene) (OlMestenOlefin) Olmestan Impurity C Dehydro Olmestan Medoxomil 4-(1-Methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-cboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester 4-(1-methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-cboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methy Olmestan Medoxomil Impurity C 4-(1-Methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1' (5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYL 1-((2-(2H-TETRAZOL-5-YL)-[1,1-BIPHENYL]-4-YL)METHYL)-4-(PROP-1-EN-2-YL)-2-PROPYL-1H-IMIDAZOLE-5-CBOXYLATE (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl] -4-yl)methyl)-4 Olmestan Medoxomilum Impurity C (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(pro UNII-227N84S103

Description	Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. Senda A, et al. Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8. Biol Pharm Bull. 2015;38(12):1975-9. [2]. Shah S, et al. Simultaneous Quantitative Analysis of Olmesartan Medoxomil and Amlodipine Besylate in Plasma by High-performance Liquid Chromatography Technique. J Young Pharm. 2012 Apr;4(2):88-94.

Molecular Formula	C₂₉H₂₈N₆O₅
Molecular Weight	540.57000
Exact Mass	540.21200
PSA	141.93000
LogP	4.97570

144689-63-4

879562-26-2

Literature: EP2426126 A1, ; Page/Page column 10-11 ;

1227626-51-8

~88%

879562-26-2

Literature: Babu, Karrothu Srihari; Tagore, Amirisetty Ravindranath; Reddy, Gade Srinivas; Venkateswarlu, Gandu; Reddy, Padi Pratap; Anand, Ramasamy Vijaya Arkivoc, 2010 , vol. 2010, # 2 p. 292 - 302

Precursor 2
144689-63-4 1227626-51-8
DownStream 0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

1917330-81-4	2138213-19-9
1270414-02-2	2304631-27-2
2304631-57-8	477709-42-5
88720-48-3	1025725-18-1
1047974-81-1	2304631-39-6