879562-26-2

879562-26-2 structure

Name: Olmesartan medoxomil impurity C
Chemical Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
CAS Number: 879562-26-2
Molecular Formula: C₂₉H₂₈N₆O₅
Molecular Weight: 540.57000
Catalog: Signaling Pathways GPCR/G Protein Angiotensin Receptor
Create Date: 2018-10-10 20:38:36
Modify Date: 2024-01-04 18:02:16
Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.

Name	(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
Synonyms	UNII-227N84S103 Dehydro Olmesartan Medoxomil olmesartan medoxomil dehydrate

Description	Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. Senda A, et al. Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8. Biol Pharm Bull. 2015;38(12):1975-9. [2]. Shah S, et al. Simultaneous Quantitative Analysis of Olmesartan Medoxomil and Amlodipine Besylate in Plasma by High-performance Liquid Chromatography Technique. J Young Pharm. 2012 Apr;4(2):88-94.

Molecular Formula	C₂₉H₂₈N₆O₅
Molecular Weight	540.57000
Exact Mass	540.21200
PSA	141.93000
LogP	4.97570

144689-63-4

879562-26-2

Literature: EP2426126 A1, ; Page/Page column 10-11 ;

1227626-51-8

~88%

879562-26-2

Literature: Babu, Karrothu Srihari; Tagore, Amirisetty Ravindranath; Reddy, Gade Srinivas; Venkateswarlu, Gandu; Reddy, Padi Pratap; Anand, Ramasamy Vijaya Arkivoc, 2010 , vol. 2010, # 2 p. 292 - 302

Precursor 2
144689-63-4 1227626-51-8
DownStream 0

879562-26-2	1392475-91-0
157356-74-6	2101308-74-9
2101308-73-8	1227626-51-8
172875-98-8	896419-17-3
144689-63-4	1127298-67-2