TMPH hydrochloride

Modify Date: 2024-04-05 19:00:42

TMPH hydrochloride Structure
TMPH hydrochloride structure
Common Name TMPH hydrochloride
CAS Number 849461-91-2 Molecular Weight 305.88
Density N/A Boiling Point N/A
Molecular Formula C16H32ClNO2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of TMPH hydrochloride


nAChR-IN-1 (hydrochloride) is a tetramethylpiperidine heptanoate, a selective nicotinic acetylcholine receptor (nAChR) inhibitor that inhibits nAChRs lacking α5, α6, or β3 subunits. nAChR-IN-1 has the effect of preventing nerve disorder, can be used for nicotinic acetylcholine receptor dysfunction or neurological disorders research[1].

 Names

Name 2,2,6,6-Tetramethyl-4-piperidinyl heptanoate hydrochloride (1:1)

 TMPH hydrochloride Biological Activity

Description nAChR-IN-1 (hydrochloride) is a tetramethylpiperidine heptanoate, a selective nicotinic acetylcholine receptor (nAChR) inhibitor that inhibits nAChRs lacking α5, α6, or β3 subunits. nAChR-IN-1 has the effect of preventing nerve disorder, can be used for nicotinic acetylcholine receptor dysfunction or neurological disorders research[1].
Related Catalog
References

[1]. Papke RL, et, al. Compositions et methodes d'inhibition selective des recepteurs nicotiniques de l'acetylcholine. WO2005032479A2

 Chemical & Physical Properties

Molecular Formula C16H32ClNO2
Molecular Weight 305.88
Exact Mass 305.21200
PSA 38.33000
LogP 4.94000

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H317-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
RIDADR NONH for all modes of transport

 Articles1

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Levamisole-induced reduction in seizure threshold: a possible role of nicotinic acetylcholine receptor-mediated pathway.

Naunyn Schmiedebergs Arch. Pharmacol. 382(3) , 279-85, (2010)

Levamisole produces seizures in man and is also known to activate the neuronal nicotinic acetylcholine receptors, which are further known to elicit seizure activity. Therefore, the present study has b...