6-Methoxy-8-nitroquinoline structure
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Common Name | 6-Methoxy-8-nitroquinoline | ||
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CAS Number | 85-81-4 | Molecular Weight | 204.182 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 373.1±27.0 °C at 760 mmHg | |
Molecular Formula | C10H8N2O3 | Melting Point | 158-160 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 179.4±23.7 °C | |
Symbol |
GHS07, GHS08 |
Signal Word | Warning |
Name | 6-Methoxy-8-nitroquinoline |
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Synonym | More Synonyms |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 373.1±27.0 °C at 760 mmHg |
Melting Point | 158-160 °C(lit.) |
Molecular Formula | C10H8N2O3 |
Molecular Weight | 204.182 |
Flash Point | 179.4±23.7 °C |
Exact Mass | 204.053497 |
PSA | 67.94000 |
LogP | 1.86 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.646 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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Symbol |
GHS07, GHS08 |
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Signal Word | Warning |
Hazard Statements | H302 + H312 + H332-H315-H319-H335-H351 |
Precautionary Statements | P261-P280-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R20/21/22;R36/37/38;R40 |
Safety Phrases | S26-S27-S36/37/39 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | VC0365000 |
HS Code | 2933499090 |
~40% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Wyeth Patent: US2003/32645 A1, 2003 ; US 20030032645 A1 |
~17% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430 |
~% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Zhurnal Obshchei Khimii, , vol. 3, p. 769,776 Archiv der Pharmazie (Weinheim, Germany), , vol. 271, p. 359,364 Chem. Zentralbl., , vol. 105, # II p. 2227 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 9, p. 304,314 Chem. Zentralbl., , vol. 107, # II p. 1543 Journal of Organic Chemistry, , vol. 12, p. 435 Journal of Organic Chemistry, , vol. 13, p. 937 |
~% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Organic Syntheses, , vol. 27, p. 48,52 DE486079 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2684 DE451730 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 15, p. 1429 |
~% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Journal of Organic Chemistry, , vol. 12, p. 435 Journal of Organic Chemistry, , vol. 13, p. 937 |
~% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 16 p. 2425 - 2430 |
~% 6-Methoxy-8-nit... CAS#:85-81-4 |
Literature: Zhurnal Obshchei Khimii, , vol. 3, p. 769,776 Archiv der Pharmazie (Weinheim, Germany), , vol. 271, p. 359,364 Chem. Zentralbl., , vol. 105, # II p. 2227 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 9, p. 304,314 Chem. Zentralbl., , vol. 107, # II p. 1543 |
~%
Detail
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Literature: Journal of the American Chemical Society, , vol. 70, p. 254 |
HS Code | 2933499090 |
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Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Ring-substituted quinolines as potential anti-tuberculosis agents.
Bioorg. Med. Chem. 12(10) , 2501-8, (2004) We report in vitro antimycobacterial properties of ring-substituted quinolines (series 1-4) constituting 56 analogues against drug-sensitive and drug-resistant M. tuberculosis H37Rv strains. The most ... |
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Primaquine-induced hemolytic anemia: formation and hemotoxicity of the arylhydroxylamine metabolite 6-methoxy-8-hydroxylaminoquinoline.
J. Pharmacol. Exp. Ther. 297(2) , 509-15, (2001) Primaquine is an important antimalarial agent because of its activity against exoerythrocytic forms of Plasmodium spp. However, methemoglobinemia and hemolytic anemia are dose-limiting side effects of... |
6-Methoxy-8-nitroquinoline |
Quinoline, 6-methoxy-8-nitro- |
MFCD00006802 |
EINECS 201-633-7 |