Osteocalcin (45-49) (human)

Modify Date: 2025-08-26 11:33:04

Osteocalcin (45-49) (human) Structure
Osteocalcin (45-49) (human) structure
 Common Name Osteocalcin (45-49) (human)
CAS Number 85679-70-5 Molecular Weight 581.66000
Density N/A Boiling Point N/A
Molecular Formula C30H39N5O7 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Osteocalcin (45-49) (human)


Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo[1].

 Names

Name 2-[[1-[2-[[2-[(2-amino-3-phenylpropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoic acid
Synonym More Synonyms

 Osteocalcin (45-49) (human) Biological Activity

Description Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo[1].
Related Catalog
In Vitro Bovine bone Gla protein (BGP) (1 nM-10 μM) exerts chemotactic activity of (0.1 and 1 μM) cultured human breast cancer cells (MDA-MB-231 cells), (1 nM-1 μM) human peripheral blood monocytes, and (1-10 μM) rat osteosarcoma cells with osteoblast-like characteristics[1].
References

[1]. Mundy GR, et al. Chemotactic activity of the gamma-carboxyglutamic acid containing protein in bone. Calcif Tissue Int. 1983;35(2):164-8.  

 Chemical & Physical Properties

Molecular Formula C30H39N5O7
Molecular Weight 581.66000
Exact Mass 581.28500
PSA 191.16000
LogP 2.13300

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

OSTEOCALCIN,Fragment 45-49
Phe-Tyr-Gly-Pro-Val
Osteocalcin Fragment 45-49 human
FYGPV
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