(11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione

Modify Date: 2025-08-25 19:08:44

(11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione Structure
(11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione structure
Common Name (11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione
CAS Number 86002-90-6 Molecular Weight 378.459
Density 1.4±0.1 g/cm3 Boiling Point 615.9±55.0 °C at 760 mmHg
Molecular Formula C21H30O6 Melting Point N/A
MSDS N/A Flash Point 340.3±28.0 °C

 Use of (11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione


18-Hydroxycortisol is an endogenous steroid that secreted by the adrenal cortex. 18-Hydroxycortisol is a cortisol derivative and a steroidogenic intermediate. 18-Hydroxycortisol can be used for primary aldosteronism (PA) research[1].

 Names

Name 18-Hydroxycortisol
Synonym More Synonyms

  Biological Activity

Description 18-Hydroxycortisol is an endogenous steroid that secreted by the adrenal cortex. 18-Hydroxycortisol is a cortisol derivative and a steroidogenic intermediate. 18-Hydroxycortisol can be used for primary aldosteronism (PA) research[1].
Related Catalog
References

[1]. Mosso L, et al. Serum 18-hydroxycortisol in primary aldosteronism, hypertension, and normotensives. Hypertension. 2001 Sep;38(3 Pt 2):688-91.  

[2]. Freel EM, et al. Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects. J Clin Endocrinol Metab. 2004 Sep;89(9):4628-33.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 615.9±55.0 °C at 760 mmHg
Molecular Formula C21H30O6
Molecular Weight 378.459
Flash Point 340.3±28.0 °C
Exact Mass 378.204254
LogP 0.36
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.614

 Synonyms

18-Hydroxycortisol
(11β,17α)-11,17,18,21-Tetrahydroxypregn-4-ene-3,20-dione
Pregn-4-ene-3,20-dione, 11,17,18,21-tetrahydroxy-, (11β,17α)-
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