7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Modify Date: 2024-01-02 22:23:23

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid structure	Common Name	7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
	CAS Number	86393-33-1	Molecular Weight	281.667
	Density	1.7±0.1 g/cm3	Boiling Point	467.3±45.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₉ClFNO₃	Melting Point	242-245 °C(lit.)
	MSDS	Chinese USA	Flash Point	236.4±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Common Name	7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS Number	86393-33-1	Molecular Weight	281.667
Density	1.7±0.1 g/cm3	Boiling Point	467.3±45.0 °C at 760 mmHg
Molecular Formula	C₁₃H₉ClFNO₃	Melting Point	242-245 °C(lit.)
MSDS	Chinese USA	Flash Point	236.4±28.7 °C
Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1].

Name	7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Synonym	More Synonyms

Description	Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial

Density	1.7±0.1 g/cm3
Boiling Point	467.3±45.0 °C at 760 mmHg
Melting Point	242-245 °C(lit.)
Molecular Formula	C₁₃H₉ClFNO₃
Molecular Weight	281.667
Flash Point	236.4±28.7 °C
Exact Mass	281.025513
PSA	59.30000
LogP	2.16
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.683
Storage condition	-20°C Freezer

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB1993795

CHEMICAL NAME :: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-

CAS REGISTRY NUMBER :: 86393-33-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H9-Cl-F-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 583 mg/kg

TOXIC EFFECTS :: Skin and Appendages - hair

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >677 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H412
Precautionary Statements	P273
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R52/53
Safety Phrases	S26-S36-S61-S22
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	VB1993795
HS Code	2933499090

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~68%

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Literature: Synthetic Communications, , vol. 12, # 8 p. 647 - 650

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HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid. Song J, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 60(4) , o503-o504, (2004)

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-

T66 BN EVJ DVQ HF IG B- AL3TJ

7-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid

MFCD00792458

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

7-Chloro-1-cyclopropyl-6-fluoro-4-oxyhydroquinoline-3-carboxylic acid

EINECS 405-050-0

7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Use of 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

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