BMS-663068

Modify Date: 2024-01-03 09:50:05

BMS-663068 structure	Common Name	BMS-663068
	CAS Number	864953-29-7	Molecular Weight	583.490
	Density	1.6±0.1 g/cm3	Boiling Point	904.1±75.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₂₆N₇O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	500.6±37.1 °C

Use of BMS-663068

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.

Name	[3-[2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl]-4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-yl]methyl dihydrogen phosphate
Synonym	More Synonyms

Description	Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1[1]
In Vivo	Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent[1].
References	[1]. Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507.

Density	1.6±0.1 g/cm3
Boiling Point	904.1±75.0 °C at 760 mmHg
Molecular Formula	C₂₅H₂₆N₇O₈P
Molecular Weight	583.490
Flash Point	500.6±37.1 °C
Exact Mass	583.158020
PSA	192.02000
LogP	-2.98
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.723

Fostemsavir

BMS-663068

{3-[(4-Benzoyl-1-piperazinyl)(oxo)acetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}methyl dihydrogen phosphate

1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine

CS-1059

UNII-97IQ273H4L

1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-

[3-[(4-benzoylpiperazin-1-yl)(oxo)acetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]methyl dihydrogen phosphate

DC Chemicals Limited
China
Product Name: Fostemsavir(BMS-663068)
Price: $600.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

BMS-663068 suppliers

Price: $231/10mM*1mLinDMSO

Reference only. check more BMS-663068 price

BMS-663068

Use of BMS-663068

Names

BMS-663068 Biological Activity

Chemical & Physical Properties

Synonyms