PRX-08066 Maleic acid

Modify Date: 2024-01-24 17:47:53

PRX-08066 Maleic acid Structure
PRX-08066 Maleic acid structure
Common Name PRX-08066 Maleic acid
CAS Number 866206-55-5 Molecular Weight 517.96
Density N/A Boiling Point N/A
Molecular Formula C23H21ClFN5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PRX-08066 Maleic acid


PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries.

 Names

Name 5-({4-[(6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl} methyl)-2-fluorobenzonitrile (2Z)-2-butenedioate (1:1)
Synonym More Synonyms

 PRX-08066 Maleic acid Biological Activity

Description PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries.
Related Catalog
Target

5-HT2B Receptor:3.4 nM (IC50)

 Chemical & Physical Properties

Molecular Formula C23H21ClFN5O4S
Molecular Weight 517.96
Exact Mass 517.098694
PSA 167.68000
LogP 4.15468
Storage condition -20℃

 Synonyms

Benzonitrile, 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl]methyl]-2-fluoro-, (2Z)-2-butenedioate (1:1)
5-({4-[(6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl}methyl)-2-fluorobenzonitrile (2Z)-2-butenedioate (1:1)
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