3,4,5-Tricaffeoylquinic acid
Modify Date: 2025-08-20 18:17:12
3,4,5-Tricaffeoylquinic acid structure
|
Common Name | 3,4,5-Tricaffeoylquinic acid | ||
|---|---|---|---|---|
| CAS Number | 86632-03-3 | Molecular Weight | 678.59 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 916.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C34H30O15 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 290.9±27.8 °C | |
Use of 3,4,5-Tricaffeoylquinic acid3,4,5-Tricaffeoylquinic acid is isolated from barks of Ilex rotunda Thunb, used in the research of the pro-inflammatory mediator-induced skin disease[1]. |
| Name | (3R,5R)-3,4,5-tris[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1-hydroxycyclohexane-1-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 3,4,5-Tricaffeoylquinic acid is isolated from barks of Ilex rotunda Thunb, used in the research of the pro-inflammatory mediator-induced skin disease[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 3,4,5-Tricaffeoylquinic acid (0-50 μM) reduces TNF-α-induced production of cytokines in HEK001 keratinocytes[1]. 3,4,5-Tricaffeoylquinic acid (15 μM, 35 min) inhibits TNF-α-induced IkBα phosphorylation and activation of NF-κB[1]. Cell Viability Assay[1] Cell Line: Keratinocytes Concentration: 15, 25 and 50 μM Incubation Time: 24 hours Result: Cell death was cell ∼4-5% at 15 and 25 μM, ∼9% at 50 μM. Western Blot Analysis[1] Cell Line: Keratinocytes Concentration: 15 μM Incubation Time: 20 min before 10 ng/mL TNF-α addition for 15 min Result: Decreased TNF-α-induced-IkBα phosphorylation of IkBα and levels of cytosolic NF-Κb p65, cytosolic NF-Κb p65. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 916.0±65.0 °C at 760 mmHg |
| Molecular Formula | C34H30O15 |
| Molecular Weight | 678.59 |
| Flash Point | 290.9±27.8 °C |
| Exact Mass | 678.158447 |
| PSA | 257.81000 |
| LogP | 2.68 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.737 |
| Storage condition | 2-8°C |
| Cyclohexanecarboxylic acid, 3,4,5-tris(((2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1-hydroxy-, (1α,3R,4α,5R)- |
| (3R,5R)-3,4,5-Tris{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1-hydroxycyclohexanecarboxylic acid |
| 3,4,5-tricaffeoylquinic acid |
| 3,4,5-tri-CQA |
| Cyclohexanecarboxylic acid, 3,4,5-tris[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1-hydroxy-, (3R,5R)- |
| Caffeoylquinic acid der. |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 3,4,5-Tricaffeoylquinic acid
- Price: Check
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 3,4,5-Tricaffeoylquinic acid
- Price: ￥4868.0/5mg ￥7268.0/20mg
- Purity: 98.0%
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- DC Chemicals Limited
- China
- Product Name: 3,4,5-tri-cqa
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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