U-62066

Modify Date: 2024-04-05 17:45:17

U-62066 Structure
U-62066 structure
Common Name U-62066
CAS Number 87151-85-7 Molecular Weight 425.39200
Density N/A Boiling Point N/A
Molecular Formula C22H30Cl2N2O2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of U-62066


Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects..

 Names

Name 2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H30Cl2N2O2
Molecular Weight 425.39200
Exact Mass 424.16800
PSA 32.78000
LogP 4.49830

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles29

More Articles
Early role of the κ opioid receptor in ethanol-induced reinforcement.

Physiol. Behav. 105(5) , 1231-41, (2012)

Effects of early ethanol exposure on later ethanol intake emphasize the importance of understanding the neurobiology of ethanol-induced reinforcement early in life. Infant rats exhibit ethanol-induced...

Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).

Mol. Vis. 17 , 1405-13, (2011)

To characterize the effects of circadian rhythm, feeding time, age, general anesthesia, and ocular hypotensive compounds on intraocular pressure (IOP) of the Tibetan monkey (Macaca thibetana).Tibetan ...

Pharmacological characterization of 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a high-affinity antagonist selective for κ-opioid receptors.

J. Pharmacol. Exp. Ther. 339 , 555-566, (2011)

2-Methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242) is a novel κ-opioid receptor (KOR) antagonist with high affinity for human (3 nM), rat (21 nM), and mouse (22...

 Synonyms

spiradoline
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