U-62066
U-62066 structure
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Common Name | U-62066 | ||
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| CAS Number | 87151-85-7 | Molecular Weight | 425.39200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H30Cl2N2O2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of U-62066Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects.. |
| Name | 2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide |
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| Synonym | More Synonyms |
| Molecular Formula | C22H30Cl2N2O2 |
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| Molecular Weight | 425.39200 |
| Exact Mass | 424.16800 |
| PSA | 32.78000 |
| LogP | 4.49830 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Early role of the κ opioid receptor in ethanol-induced reinforcement.
Physiol. Behav. 105(5) , 1231-41, (2012) Effects of early ethanol exposure on later ethanol intake emphasize the importance of understanding the neurobiology of ethanol-induced reinforcement early in life. Infant rats exhibit ethanol-induced... |
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Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).
Mol. Vis. 17 , 1405-13, (2011) To characterize the effects of circadian rhythm, feeding time, age, general anesthesia, and ocular hypotensive compounds on intraocular pressure (IOP) of the Tibetan monkey (Macaca thibetana).Tibetan ... |
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Pharmacological characterization of 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a high-affinity antagonist selective for κ-opioid receptors.
J. Pharmacol. Exp. Ther. 339 , 555-566, (2011) 2-Methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242) is a novel κ-opioid receptor (KOR) antagonist with high affinity for human (3 nM), rat (21 nM), and mouse (22... |
| spiradoline |