Trityl-PEG10-azide

Modify Date: 2024-01-10 18:23:06

Trityl-PEG10-azide Structure
Trityl-PEG10-azide structure
Common Name Trityl-PEG10-azide
CAS Number 877239-08-2 Molecular Weight 725.868
Density N/A Boiling Point N/A
Molecular Formula C39H55N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trityl-PEG10-azide


Trityl-PEG10-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Trityl-PEG9-Azide
Synonym More Synonyms

 Trityl-PEG10-azide Biological Activity

Description Trityl-PEG10-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C39H55N3O10
Molecular Weight 725.868
Exact Mass 725.388733
LogP 3.18

 Synonyms

31-Azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontane
MFCD22683292
2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontane, 31-azido-1,1,1-triphenyl-
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