Trityl-PEG8-azide

Modify Date: 2024-01-09 17:46:08

Trityl-PEG8-azide Structure
Trityl-PEG8-azide structure
Common Name Trityl-PEG8-azide
CAS Number 1818294-30-2 Molecular Weight 637.763
Density N/A Boiling Point N/A
Molecular Formula C35H47N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trityl-PEG8-azide


Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Trityl-PEG7-Azide
Synonym More Synonyms

 Trityl-PEG8-azide Biological Activity

Description Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C35H47N3O8
Molecular Weight 637.763
Exact Mass 637.336304
LogP 3.90

 Synonyms

25-Azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosane
MFCD22683296
2,5,8,11,14,17,20,23-Octaoxapentacosane, 25-azido-1,1,1-triphenyl-
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