3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE

Modify Date: 2024-01-04 16:17:33

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure
3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE structure
Common Name 3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE
CAS Number 877400-66-3 Molecular Weight 450.33700
Density 1.475g/cm3 Boiling Point 599.177ºC at 760 mmHg
Molecular Formula C21H22Cl2FN5O Melting Point N/A
MSDS N/A Flash Point 316.171ºC

 Names

Name 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.475g/cm3
Boiling Point 599.177ºC at 760 mmHg
Molecular Formula C21H22Cl2FN5O
Molecular Weight 450.33700
Flash Point 316.171ºC
Exact Mass 449.11900
PSA 77.99000
LogP 5.94770
Index of Refraction 1.673

 Safety Information

HS Code 2933990090

 Synthetic Route

~86%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: TELIGENE LTD.; ZHANG, Dawei Patent: WO2013/41038 A1, 2013 ; Location in patent: Page/Page column 24 ;

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

~%

3-(1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE Structure

3-(1-(2,6-DICHL...

CAS#:877400-66-3

Literature: Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6342 - 6363

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
3-(1-(2,6-dichloro-3-fluoro-phenyl)ethoxy)-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-amine
Kinome_3145
Kinome_3144
Kinome_3143
BOCCHEM BC-L-Y016
2-PYRIDINAMINE,3-[1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY]-5-[1-(4-PIPERIDINYL)-1H-PYRAZOL-4-YL]
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