METANEPHRINEHYDROCHLORIDE

Modify Date: 2024-01-02 18:39:49

METANEPHRINEHYDROCHLORIDE Structure
METANEPHRINEHYDROCHLORIDE structure
Common Name METANEPHRINEHYDROCHLORIDE
CAS Number 881-95-8 Molecular Weight 233.692
Density N/A Boiling Point 378.8ºC at 760 mmHg
Molecular Formula C10H16ClNO3 Melting Point 180-182ºC
MSDS Chinese USA Flash Point 182.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-(1-Hydroxy-2-(methylamino)ethyl)-2-methoxyphenol hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 378.8ºC at 760 mmHg
Melting Point 180-182ºC
Molecular Formula C10H16ClNO3
Molecular Weight 233.692
Flash Point 182.9ºC
Exact Mass 233.081863
PSA 61.72000
LogP 1.84650
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA4798000
CHEMICAL NAME :
Benzenemethanol, 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
881-95-8
LAST UPDATED :
199412
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H15-N-O3.Cl-H
MOLECULAR WEIGHT :
233.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
840 mg/kg/42D-I
TOXIC EFFECTS :
Cardiac - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,315,1973

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
HS Code 2922509090

 Synthetic Route

~69%

METANEPHRINEHYDROCHLORIDE Structure

METANEPHRINEHYD...

CAS#:881-95-8

Literature: Kulikov, S. V.; Samartsev, M. A. Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 2 p. 348 - 358

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METANEPHRINEHYDROCHLORIDE Structure

METANEPHRINEHYD...

CAS#:881-95-8

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, , vol. 28, # 2 p. 348 - 358

~%

METANEPHRINEHYDROCHLORIDE Structure

METANEPHRINEHYD...

CAS#:881-95-8

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, , vol. 28, # 2 p. 348 - 358

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1

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Membrane proteins are important drug targets in many human diseases and gathering structural information regarding these proteins encourages the pharmaceutical industry to develop new molecules using ...

 Synonyms

4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride (1:1)
Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]-, (αR)-, hydrochloride (1:1)
dl-m-o-methylepinephrine hydrochloride
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