c-Fms-IN-1

Modify Date: 2026-08-05 10:23:54

c-Fms-IN-1 structure	Common Name	c-Fms-IN-1
	CAS Number	885703-64-0	Molecular Weight	393.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₇N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of c-Fms-IN-1

c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1].

Name	c-Fms-IN-1

Description	c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
Target	FMS kinase[1]
References	[1]. Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.

Molecular Formula	C₂₂H₂₇N₅O₂
Molecular Weight	393.48
InChIKey	UUPPIQKPNBIUKY-UHFFFAOYSA-N
SMILES	CN1CCN(c2ccc(NC(=O)c3ccc(C#N)o3)c(N3CCCCC3)c2)CC1
Storage condition	2-8℃

Name: Toxicity in mouse liver microsomes assessed as glutathione conjugate formation at 20 ...
Source: ChEMBL
Target: Liver
External Id: CHEMBL933667

Name: Drug distribution in mouse brain at 30 mg/kg, po measured after 60 mins
Source: ChEMBL
Target: N/A
External Id: CHEMBL5524454

Name: Toxicity in mouse liver microsomes assessed as amide bond cleavage product at 20 or 4...
Source: ChEMBL
Target: Liver
External Id: CHEMBL933668

Name: Volume of distribution in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL927239

Name: Oral bioavailability in CD1 mouse at 10 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL927240

Name: Inhibition of CSF1R (unknown origin)
Source: ChEMBL
Target: Macrophage colony-stimulating factor 1 receptor
External Id: CHEMBL5524445

Name: Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins...
Source: ChEMBL
Target: Macrophage colony-stimulating factor 1 receptor
External Id: CHEMBL927234

Name: Inhibition of FMS-induced proliferation of bone marrow derived human macrophages
Source: ChEMBL
Target: Macrophage
External Id: CHEMBL927235

Name: Half life in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL927237

Name: Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80...
Source: ChEMBL
Target: Macrophage colony-stimulating factor 1 receptor
External Id: CHEMBL2163155

Total 10, Current Page 1 of 1

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: c-Fms-IN-1?
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

c-Fms-IN-1 suppliers

c-Fms-IN-1 price

c-Fms-IN-1

Use of c-Fms-IN-1

Names

c-Fms-IN-1 Biological Activity

Chemical & Physical Properties

c-Fms-IN-1Bioassay

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.