Tricaine methanesulfonate

Modify Date: 2024-01-02 12:28:14

Tricaine methanesulfonate Structure
Tricaine methanesulfonate structure
Common Name Tricaine methanesulfonate
CAS Number 886-86-2 Molecular Weight 261.295
Density N/A Boiling Point 305-310
Molecular Formula C10H15NO5S Melting Point 146-149 °C(lit.)
MSDS Chinese USA Flash Point 151.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Tricaine methanesulfonate


Tricaine methanesulfonate (MS-222) possesses anesthetic effect. Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures[1].

 Names

Name Tricaine methanesulfonate
Synonym More Synonyms

 Tricaine methanesulfonate Biological Activity

Description Tricaine methanesulfonate (MS-222) possesses anesthetic effect. Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures[1].
Related Catalog
In Vitro Tricaine methanesulfonate in powder form easily can become airborne and could become hazardous to the handler[1]. Tricaine methanesulfonate (TMS) solution is photosensitive (its color changes with light exposure), although the color change does not necessarily indicate significant activity decrease and thus color should not be used to gauge degradation[1].
References

[1]. Kathleen M. Carter, et al. A review of tricaine methanesulfonate for anesthesia of fish. Reviews in Fish Biology and Fisheries volume 21, pages51–59(2011).

 Chemical & Physical Properties

Boiling Point 305-310
Melting Point 146-149 °C(lit.)
Molecular Formula C10H15NO5S
Molecular Weight 261.295
Flash Point 151.2ºC
Exact Mass 261.067108
PSA 115.07000
LogP 2.61150
Storage condition 2-8°C
Water Solubility H2O: 50 mg/mL, clear, colorless

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG2455000
CHEMICAL NAME :
Benzoic acid, 3-amino-, ethyl ester, methanesulfonate
CAS REGISTRY NUMBER :
886-86-2
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H11-N-O2.C-H4-O3-S
MOLECULAR WEIGHT :
261.32
WISWESSER LINE NOTATION :
ZR CVO2 &WSQ1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03233
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 16,252,1974

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG2455000
HS Code 2923900090

 Customs

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles325

More Articles
Denervation impairs regeneration of amputated zebrafish fins.

BMC Dev. Biol. 14(1) , 49, (2015)

Zebrafish are able to regenerate many of its tissues and organs after damage. In amphibians this process is regulated by nerve fibres present at the site of injury, which have been proposed to release...

Toll-Like Receptor 9 Alternatively Spliced Isoform Negatively Regulates TLR9 Signaling in Teleost Fish.

PLoS ONE 10 , e0126388, (2015)

Toll-like receptor 9 (TLR9) recognizes and binds unmethylated CpG motifs in DNA, which are found in the genomes of bacteria and DNA viruses. In fish, Tlr9 is highly diverse, with the number of introns...

Molecular characterization of purinergic receptor P2X4 involved in Japanese flounder (Paralichthys olivaceus) innate immune response and its interaction with ATP release channel Pannexin1.

Fish Shellfish Immunol. 47 , 100-9, (2015)

P2X4 receptor (P2X4R) is a member of trimeric ATP-gated receptor channel family. Despite the importance of P2X4R in innate immunity has been addressed in mammals, the immunological significance of P2X...

 Synonyms

Ethyl 3-aminobenzoate methanesulfonate salt
Ethyl 3-aminobenzoate methanesulfonate
Benzoic acid, 3-amino-, ethyl ester, methanesulfonate (1:1)
Ethyl 3-aminobenzoate methanesulfonate (1:1)
Ethyl m-aminobenzoate methanesulfonate
ethyl 3-aminobenzoate,methanesulfonic acid
Benzoic acid, m-amino-, ethyl ester, methanesulfonate
Ethyl 3-aminobenzoate methanesulphonate salt
EINECS 212-956-8
MFCD00013176
Tricaine methansulphate
Tricaine mesylate
Top Suppliers:I want be here





Get all suppliers and price by the below link:

Tricaine methanesulfonate suppliers


Price: ¥550/10 mM * 1 mL in Water

Reference only. check more Tricaine methanesulfonate price