2-Propanone, 1-(2-methoxyethoxy)- (9CI)

Modify Date: 2024-01-09 16:51:55

2-Propanone, 1-(2-methoxyethoxy)- (9CI) Structure
2-Propanone, 1-(2-methoxyethoxy)- (9CI) structure
Common Name 2-Propanone, 1-(2-methoxyethoxy)- (9CI)
CAS Number 88986-89-4 Molecular Weight 132.15800
Density N/A Boiling Point N/A
Molecular Formula C6H12O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Propanone, 1-(2-methoxyethoxy)- (9CI)


PROTAC Linker 28 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 28 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name 1-(2-methoxyethoxy)propan-2-one
Synonym More Synonyms

 2-Propanone, 1-(2-methoxyethoxy)- (9CI) Biological Activity

Description PROTAC Linker 28 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 28 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C6H12O3
Molecular Weight 132.15800
Exact Mass 132.07900
PSA 35.53000
LogP 0.23840

 Safety Information

HS Code 2914509090

 Synthetic Route

~%

2-Propanone, 1-(2-methoxyethoxy)- (9CI) Structure

2-Propanone, 1-...

CAS#:88986-89-4

Literature: Dow Chem.Co. Patent: US2526545 , 1948 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

2-Propanone,1-(2-methoxyethoxy)
1-(2-methoxyethoxy)acetone
(2-Methoxy-aethoxy)-aceton
(2-methoxy-ethoxy)-acetone