Menthol

Modify Date: 2025-08-20 12:21:25

Menthol structure	Common Name	Menthol
	CAS Number	89-78-1	Molecular Weight	156.265
	Density	0.9±0.1 g/cm3	Boiling Point	215.4±8.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₂₀O	Melting Point	34-36 °C(lit.)
	MSDS	Chinese USA	Flash Point	93.3±0.0 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of Menthol

DL-Menthol is a relative configuration of (-)-Menthol. DL-Menthol induces surgical anesthesia for fish that relates to the activation of GABAA receptor[1].

Name	DL-Menthol
Synonym	More Synonyms

Description	DL-Menthol is a relative configuration of (-)-Menthol. DL-Menthol induces surgical anesthesia for fish that relates to the activation of GABAA receptor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Menthol Induces Surgical Anesthesia and Rapid Movement in Fishes. The Open Neuroscience. 2014 Feb; 8(1):1-8.

Density	0.9±0.1 g/cm3
Boiling Point	215.4±8.0 °C at 760 mmHg
Melting Point	34-36 °C(lit.)
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.265
Flash Point	93.3±0.0 °C
Exact Mass	156.151413
PSA	20.23000
LogP	3.20
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.457
Water Solubility	insoluble

Menthol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OT0350000

CHEMICAL NAME :: Menthol

CAS REGISTRY NUMBER :: 89-78-1

BEILSTEIN REFERENCE NO. :: 1902288

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C10-H20-O

MOLECULAR WEIGHT :: 156.30

WISWESSER LINE NOTATION :: L6TJ AY1&1 BQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3180 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - hallucinations, distorted perceptions Behavioral - muscle weakness

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 10,481,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 222,244,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 63,43,1939

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 63,43,1939 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 22400 mg/kg/28D-I

TOXIC EFFECTS :: Behavioral - fluid intake Liver - changes in liver weight Blood - changes in other cell count (unspecified)

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 19,207,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 44440 No. of Facilities: 3689 (estimated) No. of Industries: 36 No. of Occupations: 35 No. of Employees: 25754 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 44440 No. of Facilities: 2880 (estimated) No. of Industries: 28 No. of Occupations: 33 No. of Employees: 44233 (estimated) No. of Female Employees: 31143 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S36/37/39-S24/25-S36-S26
RIDADR	UN 1888 6.1/PG 3
WGK Germany	2
RTECS	OT0350000
HS Code	2906110000

Precursor 5
CAS#:129368-71-4 2-{[(tert-butyl... CAS#:62338-23-2 trimethyl[5-met... CAS#:72020-06-5 tetrahydro-2-[[... CAS#:5392-40-5 Citral
CAS#:106-23-0 Citronellal
DownStream 10
CAS#:497-25-6 oxazolidinone CAS#:62338-23-2 trimethyl[5-met... CAS#:141334-24-9 bis[(5-methyl-2... CAS#:498-81-7 Dihydro-α-terpineol
CAS#:21411-81-4 Cyclohexanamine... CAS#:10458-14-7 Menthone CAS#:18888-09-0 tetrakis(5-meth... CAS#:99-82-1 1-iso-Propyl-4-...
CAS#:89-83-8 Thymol CAS#:89-48-5 (-)-Menthyl Acetate

HS Code	2906110000
Summary	2906110000 2-isopropyl-5-methylcyclohexanol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:13.0%

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EINECS 216-074-4

Cyclohexanol, 2-isopropyl-5-methyl-

Menthol, dl-

D-2-amino-5-phosphonovaleric acid

Menthol (VAN)

APV

MENTHOLS

AP-5

MENTHOL CRYSTALS

DL-MENTHOL FOR SYNTHESIS

DL-APV

MENTHOL 99

(+/-)-MENTHOL

DL-MENTHAN-3-OL

RACEMIC MENTHO

DL-MENTHOL, CERTIFIED REFERENCE MATERIAL

hexahydrothymol

Menthol

rac-Menthol

2-Isopropyl-5-methylcyclohexanol

5-PHOSPHONO-DL-NORVALINE

dl-Peppermint

I-menthol

CYCLOHEXANOL,5-METHYL-2-(1-METHYLETHYL)-, (1R,2S,5R)-REL-

UNII:39PJ29YY8Z

2-isopropyl-5-methyl-cyclohexanol

p-Menthan-3-ol

(1R,2S,5R)-rel-2-Isopropyl-5-methylcyclohexanol

DL-2-amino-5-phosphonovaleric acid

Fancol menthol

Racemic menthol

4-isopropyl-1-methylcyclohexan-3-ol

DL-AP5

MENTHOL RACEMIC

5-Phosphononorvaline

2-amino-5-phosphopentanoicacid

(-a)-MENTHOL RACEMIC

2-amino-5-phosphonovaleric acid

Norvaline, 5-phosphono-

MENTHOL RAC

Cyclohexanol, 5-methyl-2-(1-methylethyl)-

MENTHOMENTHOL

MFCD00001484

2-amino-5-phosphovaleric acid

3 para menthanol

Menthacamphor

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Menthol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Menthol
Price: ￥68.0/20mg
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Menthol
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: DL-Menthol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Menthol
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Price: ￥43/25g

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Menthol

Use of Menthol

Names

Menthol Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

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Synonyms

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