MK-8776

Modify Date: 2024-01-11 03:53:05

MK-8776 Structure
MK-8776 structure
Common Name MK-8776
CAS Number 891494-64-7 Molecular Weight 376.254
Density 1.8±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H18BrN7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MK-8776


SCH900776 S-isomer is the S-isomer of SCH900776. SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM.

 Names

Name 6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
Synonym More Synonyms

 MK-8776 Biological Activity

Description SCH900776 S-isomer is the S-isomer of SCH900776. SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM.
Related Catalog

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Molecular Formula C15H18BrN7
Molecular Weight 376.254
Exact Mass 375.080688
PSA 86.06000
LogP 0.76
Index of Refraction 1.819
Storage condition 2-8℃

 Synonyms

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine
Pyrazolo[1,5-a]pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-3-piperidinyl]-
CS-1119
6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-((3S)-piperidin-3-yl)pyrazolo(1,5-a)pyrimidin-7-amine
Pyrazolo(1,5-a)pyrimidin-7-amine,6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3S)-3-piperidinyl
UNII-99Y1V29WVE
6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine
Pyrazolo[1,5-a]pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]-
MK-8776
SCH 900776
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Price: $145/10mM*1mLinDMSO

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