BRD7586

Modify Date: 2025-11-29 13:02:26

BRD7586 structure	Common Name	BRD7586
	CAS Number	895460-70-5	Molecular Weight	407.89436
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₄ClN₃O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BRD7586

BRD7586 is a cell-permeable small-molecule inhibitor of SpCas9. BRD7586 is the smallest known anti-CRISPR[1].

Name	3-(4-chlorophenyl)sulfonyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide

Description	BRD7586 is a cell-permeable small-molecule inhibitor of SpCas9. BRD7586 is the smallest known anti-CRISPR[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> CRISPR/Cas9
In Vitro	BRD7586在细胞中特异性地与 SpCas9 结合，但不与 Cas12a 结合[1]。 BRD7586 (0-20 μM; 24 h) 在 HiBiT-knock-in 试验中，呈剂量依赖性地抑制 SpCas9[1]。 BRD7586 (20 μM; 48 h) 增强 HEK293T 细胞中中靶与脱靶的比值[1]。
References	[1]. Lim D, et al. A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules. Nat Cell Biol. 2022 Dec;24(12):1766-1775.

Molecular Formula	C₁₇H₁₄ClN₃O₃S₂
Molecular Weight	407.89436
InChIKey	MLSIIIMAQNQEOV-UHFFFAOYSA-N
SMILES	O=C(CCS(=O)(=O)c1ccc(Cl)cc1)Nc1nc(-c2ccncc2)cs1

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BRD7586
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: BRD7586
Price: ￥550.0/5mg
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

BRD7586 suppliers