Urea

Modify Date: 2024-01-01 19:20:54

Urea Structure
Urea structure
 Common Name Urea
CAS Number 9002-13-5 Molecular Weight 60.055
Density 1.6±0.1 g/cm3 Boiling Point 165.1±23.0 °C at 760 mmHg
Molecular Formula C2H6 Melting Point N/A
MSDS Chinese USA Flash Point 53.7±22.6 °C
Symbol GHS07 GHS08
GHS07, GHS08		 Signal Word Danger

 Use of Urea


Urease is produced by many types of bacteria and is an effective virulence factor for some pathogenic bacteria. Urease is also central to the metabolism and virulence of Helicobacter pylori, helping it colonize the stomach lining[1].

 Names

Name Ethane
Synonym More Synonyms

 Urea Biological Activity

Description Urease is produced by many types of bacteria and is an effective virulence factor for some pathogenic bacteria. Urease is also central to the metabolism and virulence of Helicobacter pylori, helping it colonize the stomach lining[1].
Related Catalog
References

[1]. Mobley H L T, et al. Urease[J]. Helicobacter pylori: physiology and genetics, 2001: 177-191.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 165.1±23.0 °C at 760 mmHg
Molecular Formula C2H6
Molecular Weight 60.055
Flash Point 53.7±22.6 °C
Exact Mass 60.032364
LogP -1.43
Vapour Pressure 0.6±0.7 mmHg at 25°C
Index of Refraction 1.528
Storage condition 2-8°C
Water Solubility It is slightly soluble in water.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU1700000
CHEMICAL NAME :
Urease
CAS REGISTRY NUMBER :
9002-13-5
LAST UPDATED :
199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
58 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
6 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - sleep Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 206,731,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3123 No. of Facilities: 1133 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 14585 (estimated) No. of Female Employees: 9975 (estimated)

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H315-H319-H334-H335
Precautionary Statements P261-P305 + P351 + P338-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
Risk Phrases R36/37/38
Safety Phrases S22-S24-S26-S36/37-S45-S36-S23
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS YU1700000

 Articles59

More Articles
Efficiency of utilization of nitrogen coated with urease inhibitor in maize.

Pak. J. Biol. Sci. 16(17) , 871-6, (2013)

This study aimed to evaluate under field conditions the efficiency in the use ofN coated with urease inhibitor in maize. The experiment was conducted in the year of 2007/2008. The experimental design ...

Study of alpha-amylase and urease inhibitory activities of Melilotus indicus (Linn.) All.

Pak. J. Pharm. Sci. 27(1) , 57-61, (2014)

Melilotus indicus (Linn.) All. is a small herb distributed throughout Pakistan and has a number of ethnomedicinal uses. It is also consumed as a vegetable. In the present work, we are reporting the al...

Effects of the halophytes Tecticornia indica and Suaeda fruticosa on soil enzyme activities in a Mediterranean Sabkha.

Int. J. Phytoremediation 15(2) , 188-97, (2013)

In the present work, we studied the effectiveness of the predominant halophytes of Soliman sabkha (Tecticornia indica and Suaeda fruticosa) to promote soil biological activities and ecosystem producti...

 Synonyms

Carbonyl diamide
Urea
Carbamide
carbonyl diamine
MFCD00070858
Urea (8CI,9CI)
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