Polyoxyethylene lauryl ether structure
|
Common Name | Polyoxyethylene lauryl ether | ||
---|---|---|---|---|
CAS Number | 9002-92-0 | Molecular Weight | 1199.543 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 960.0±60.0 °C at 760 mmHg | |
Molecular Formula | (C2H4O)nC12H26O | Melting Point | 41-45 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 534.4±32.9 °C | |
Symbol |
GHS05, GHS07 |
Signal Word | Danger |
Use of Polyoxyethylene lauryl etherPolidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias. |
Name | Polyoxyethylene lauryl ether |
---|---|
Synonym | More Synonyms |
Description | Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias. |
---|---|
Related Catalog | |
In Vivo | Polidocanol (0.5%, 1%, and 2%) results in significantly more adhesions than tetracycline, whereas the effect of diluted polidocanol is similar to that of tetracycline in rats. The higher concentrationsof polidocanol, of 0.5%, 1%, and 2% are more effective than either the diluted polidocanol or tetracycline against pleurodesis[1]. |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 960.0±60.0 °C at 760 mmHg |
Melting Point | 41-45 °C(lit.) |
Molecular Formula | (C2H4O)nC12H26O |
Molecular Weight | 1199.543 |
Flash Point | 534.4±32.9 °C |
Exact Mass | 1198.801270 |
PSA | 232.52000 |
LogP | -2.83 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.465 |
Storage condition | Store at RT. |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 9002-92-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: clear Odor: Not available. pH: 5-7 Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: 235 deg F ( 112.78 deg C) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Soluble. Specific Gravity/Density: 1.03 Molecular Formula: Solution Molecular Weight: 0 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Excess heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 9002-92-0: JR5960000 JR5970000 JR5990000 MD0875000 LD50/LC50: CAS# 9002-92-0: Draize test, rabbit, eye: 10 mg; Draize test, rabbit, eye: 100 mg; Draize test, rabbit, eye: 750 ug/24H Severe; Draize test, rabbit, skin: 100 mg; Draize test, rabbit, skin: 500 mg/24H Mild; Draize test, rabbit, skin: 75 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Moderate; Oral, mouse: LD50 = 4940 mg/kg; Oral, mouse: LD50 = 1170 mg/kg; Oral, mouse: LD50 = 3500 mg/kg; Oral, mouse: LD50 = 1170 mg/kg; Oral, rat: LD50 = 8600 mg/kg; Oral, rat: LD50 = 4150 mg/kg; Oral, rat: LD50 = 8600 mg/kg; Oral, rat: LD50 = 1 gm/kg. Carcinogenicity: BRIJ 35, 30% w/v solution in water - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 9002-92-0: 2 Canada CAS# 9002-92-0 is listed on Canada's DSL List. CAS# 9002-92-0 is listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 9002-92-0 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS05, GHS07 |
---|---|
Signal Word | Danger |
Hazard Statements | H302-H315-H318 |
Precautionary Statements | P280-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful |
Risk Phrases | R22;R36/37/38 |
Safety Phrases | 26-39-37/39-36/37/39-36-24/25 |
RIDADR | UN 3082 9/PG 3 |
WGK Germany | 3 |
RTECS | MD0875000 |
HS Code | 34021300 |
HS Code | 34021300 |
---|
Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.
Antimicrob. Agents Chemother. 53 , 1898-906, (2009) Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have sho... |
|
Antimicrobial Nanoemulsion Formulation with Improved Penetration of Foliar Spray through Citrus Leaf Cuticles to Control Citrus Huanglongbing.
PLoS ONE 10 , e0133826, (2015) Huanglongbing (HLB) is the most serious disease affecting the citrus industry worldwide to date. The causal agent, Candidatus Liberibacter asiaticus (Las), resides in citrus phloem, which makes it dif... |
|
Selective inhibitory effects of hybrid liposomes on the growth of HIV type 1-infected cells in vitro.
Bioorg. Med. Chem. Lett. 18 , 4578-80, (2008) A good correlation between fifty-percent inhibitory concentration (IC(50)) of hybrid liposomes (HL) composed of dimyristoylphosphatidylcholine and polyoxyethylene(n) dodecyl ether on the growth of MOL... |
depeg |
EINECS 500-002-6 |
la7 |
g3711 |
ped |
bl9 |
do9 |
g3707 |
polyoxethyleneglycol-23 lauryl ether |
bl9ex |
Polidocanol (PEG Monododecyl Ether) |
yx500 |
AEO4 |
MFCD00080891 |
Brij 35 |
Polidocanol |