SEC inhibitor KL-2
Modify Date: 2024-01-06 11:30:25
SEC inhibitor KL-2 structure
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Common Name | SEC inhibitor KL-2 | ||
|---|---|---|---|---|
| CAS Number | 900308-51-2 | Molecular Weight | 333.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H13ClFNO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SEC inhibitor KL-2SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM[1]. |
| Name | SEC inhibitor KL-2 |
|---|
| Description | SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM[1]. |
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| Related Catalog | |
| Target |
SEC[1] |
| References |
| Molecular Formula | C17H13ClFNO3 |
|---|---|
| Molecular Weight | 333.74 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: SEC inhibitor KL-2
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: SEC inhibitor KL-2
- Price: $650.0/100mg $1100.0/250mg $2200.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: SEC inhibitor KL-2
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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