CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TQ8701000
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CHEMICAL NAME :
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Polyglycol laurate
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CAS REGISTRY NUMBER :
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9004-81-3
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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9
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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692 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
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REFERENCE :
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20PKA3 "Novye Dannye Po Toksikologii Redkikh Metalov Ikh Soedinenii," New Data on the Toxicology of Rare Metals and Their Compounds, Izrael'son, Z.I., ed., Moscow, Izdatel'stvo "Meditsina," 1967 Volume(issue)/page/year: -,45,1967
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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500 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 38,428,1949 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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13687 gm/kg/2Y-C
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TOXIC EFFECTS :
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Nutritional and Gross Metabolic - weight loss or decreased weight gain
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REFERENCE :
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TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2(1),59,1960
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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889 gm/kg/70D-C
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TOXIC EFFECTS :
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Gastrointestinal - hypermotility, diarrhea Related to Chronic Data - death
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REFERENCE :
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ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 34,249,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83953 No. of Facilities: 1082 (estimated) No. of Industries: 28 No. of Occupations: 49 No. of Employees: 18551 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6456 No. of Facilities: 2120 (estimated) No. of Industries: 30 No. of Occupations: 47 No. of Employees: 59440 (estimated) No. of Female Employees: 27629 (estimated)
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