2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine

Modify Date: 2025-09-26 20:12:16

2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine structure	Common Name	2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine
	CAS Number	90402-40-7	Molecular Weight	395.45200
	Density	1.246g/cm3	Boiling Point	630.3ºC at 760mmHg
	Molecular Formula	C₂₂H₂₅N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	335ºC

Use of 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine

Abanoquil (U-K52046), an potent and selective α-1 adrenoceptor antagonist, is an anti-arrhythmic agent. Abanoquil can be used for erectile dysfunction research[1][2].

Name	2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine
Synonym	More Synonyms

Description	Abanoquil (U-K52046), an potent and selective α-1 adrenoceptor antagonist, is an anti-arrhythmic agent. Abanoquil can be used for erectile dysfunction research[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	α1-adrenergic receptor
In Vivo	Abanoquil 在猴子模型体内注射时能够松弛收缩的组织条并诱导勃起反应[1]。
References	[1]. A Giraldi, et al. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. Int J Impot Res. 2000 Mar;12(S1):S37-S40. [2]. T C Tham, et al. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. Br J Clin Pharmacol. 1992 Apr;33(4):405-9.

Density	1.246g/cm3
Boiling Point	630.3ºC at 760mmHg
Molecular Formula	C₂₂H₂₅N₃O₄
Molecular Weight	395.45200
Flash Point	335ºC
Exact Mass	395.18500
PSA	79.07000
LogP	4.06030

N/A

CAS#:90402-41-8

~47%

2-(6,7-dimethox...

CAS#:90402-40-7

Literature: Campbell, Simon F.; Hardstone, J. David; Palmer, Michael, J. Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4813 - 4816

2-Amino-4,5-dim...

CAS#:26961-27-3

2-(6,7-dimethox...

CAS#:90402-40-7

Literature: Campbell, Simon F.; Hardstone, J. David; Palmer, Michael, J. Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4813 - 4816

6,7-Dimethoxy-1...

CAS#:1745-07-9

2-(6,7-dimethox...

CAS#:90402-40-7

Literature: Campbell, Simon F.; Hardstone, J. David; Palmer, Michael, J. Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4813 - 4816

ethyl N-(2-cyan...

CAS#:90402-53-2

2-(6,7-dimethox...

CAS#:90402-40-7

Literature: Campbell, Simon F.; Hardstone, J. David; Palmer, Michael, J. Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4813 - 4816

1-(6,7-dimethox...

CAS#:26163-70-2

2-(6,7-dimethox...

CAS#:90402-40-7

Literature: Campbell, Simon F.; Hardstone, J. David; Palmer, Michael, J. Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4813 - 4816

4-amino-6,7-dimethoxy-2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinol-2-yl)quinoline

UNII-F738MWY53L

Abanoquil

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Abanoquil
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥2500/5 mg

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2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine

Use of 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinolin-4-amine

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