beta-D-Glucan

Modify Date: 2024-01-02 11:53:06

beta-D-Glucan structure	Common Name	beta-D-Glucan
	CAS Number	9041-22-9	Molecular Weight	504.437
	Density	1.8±0.1 g/cm3	Boiling Point	865.2±65.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₃₂O₁₆	Melting Point	N/A
	MSDS	USA	Flash Point	477.0±34.3 °C

Use of beta-D-Glucan

β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].

Name	β-D-Glucan
Synonym	More Synonyms

Description	β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer
In Vitro	β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC50 of ∼164 μg/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC50 values of 4.6 and 24.2 μg/mL, respectively[3].
References	[1]. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. [2]. Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. [3]. Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44(4):1365-1375.

Density	1.8±0.1 g/cm3
Boiling Point	865.2±65.0 °C at 760 mmHg
Molecular Formula	C₁₈H₃₂O₁₆
Molecular Weight	504.437
Flash Point	477.0±34.3 °C
Exact Mass	504.169037
PSA	268.68000
LogP	-3.25
Appearance of Characters	powder
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.673
Storage condition	2-8°C
Water Solubility	H2O: 20 mg/mL, clear, faintly yellow

beta-D-Glucan MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	LZ3985000

(1,3)-β-D-glucan as a prognostic marker of treatment response in invasive candidiasis.

Clin. Infect. Dis. 55(4) , 521-6, (2012)

(1,3)-β-D-glucan (BG) is a biomarker for invasive candidiasis (IC). The usefulness of BG level as a prognostic marker of treatment outcome is not well characterized.Two hundred fifty-seven patients wi...

β-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose

Carbamic acid,(1,1-dimethyl-2-propynyl)-,2-fluoroethyl ester

α-D-xylo-Hexopyranose, O-β-D-glucopyranosyl-(1->4)-O(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-, (4ξ)-

beta-D-Glucan