NSC 694623

Modify Date: 2025-08-23 10:48:15

NSC 694623 Structure
NSC 694623 structure
Common Name NSC 694623
CAS Number 907957-34-0 Molecular Weight 284.38
Density N/A Boiling Point N/A
Molecular Formula C16H16N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSC 694623


NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer[1].

 Names

Name NSC 694623

 NSC 694623 Biological Activity

Description NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer[1].
Related Catalog
Target

PCAF:15.9 μM (IC50)

In Vitro NSC 694623 has antiproliferative activity against SK-N-SH with an IC50 of 8.93 μM, and inhibits 21% of HCT116 at 25 μM[1].
References

[1]. Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.

 Chemical & Physical Properties

Molecular Formula C16H16N2OS
Molecular Weight 284.38
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