Benzyl-PEG10-alcohol

Modify Date: 2024-01-02 17:26:50

Benzyl-PEG10-alcohol Structure
Benzyl-PEG10-alcohol structure
Common Name Benzyl-PEG10-alcohol
CAS Number 908258-44-6 Molecular Weight 548.66300
Density N/A Boiling Point N/A
Molecular Formula C27H48O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG10-alcohol


Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Benzyl-PEG10-alcohol Biological Activity

Description Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H48O11
Molecular Weight 548.66300
Exact Mass 548.32000
PSA 112.53000
LogP 1.34490

 Synthetic Route

~%

Benzyl-PEG10-alcohol Structure

Benzyl-PEG10-alcohol

CAS#:908258-44-6

Literature: CHUGAI SEIYAKU KABUSHIKI KAISHA Patent: EP1854792 A1, 2007 ; Location in patent: Page/Page column 207-208 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

decaethylene glycol monobenzyl ether
1-Phenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-ol