(±)20-HDHA

Modify Date: 2024-01-06 18:05:59

(±)20-HDHA Structure
(±)20-HDHA structure
Common Name (±)20-HDHA
CAS Number 90906-41-5 Molecular Weight 344.488
Density 1.0±0.1 g/cm3 Boiling Point 500.2±50.0 °C at 760 mmHg
Molecular Formula C22H32O3 Melting Point N/A
MSDS N/A Flash Point 270.4±26.6 °C

 Use of (±)20-HDHA


(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate[1][2][3].

 Names

Name 20-hydroxydocosa-4,7,10,13,16,18-hexaenoic acid
Synonym More Synonyms

 (±)20-HDHA Biological Activity

Description (±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate[1][2][3].
Related Catalog
In Vitro Numerous reports demonstrate the beneficial effects of fish oil on human diseases such as arthritis, Alzheimer’s disease, lung fibrosis, and inflammatory bowel diseases. As an essential omega-3 polyunsaturated fatty acid, Docosahexaenoic acid (DHA) is a major component of fish oil[3].
References

[1]. VanRollins M, et al. Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate. J Lipid Res. 1984 May;25(5):507-17.

[2]. Kim HY, et al. Stereochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate. Prostaglandins. 1990 Nov;40(5):473-90.

[3]. Hong S, et al. Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms. J Am Soc Mass Spectrom. 2007 Jan;18(1):128-44.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 500.2±50.0 °C at 760 mmHg
Molecular Formula C22H32O3
Molecular Weight 344.488
Flash Point 270.4±26.6 °C
Exact Mass 344.235138
PSA 57.53000
LogP 5.09
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.533

 Synonyms

4,7,10,13,16,18-Docosahexaenoic acid, 20-hydroxy-, (4Z,7Z,10Z,13Z,16Z,18E)-
(4Z,7Z,10Z,13Z,16Z,18E)-20-Hydroxy-4,7,10,13,16,18-docosahexaenoic acid
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