13C15-Nivalenol

Modify Date: 2025-08-25 13:45:54

13C15-Nivalenol Structure
13C15-Nivalenol structure
Common Name 13C15-Nivalenol
CAS Number 911392-40-0 Molecular Weight 327.20
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula 13C15H20O7 Melting Point N/A
MSDS N/A Flash Point 35.6 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of 13C15-Nivalenol


Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3].

 Names

Name 13C15-Nivalenol
Synonym More Synonyms

 13C15-Nivalenol Biological Activity

Description Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3].
Related Catalog
Target

caspase[2]

In Vitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula 13C15H20O7
Molecular Weight 327.20
Exact Mass 327.171234
Index of Refraction 1.658

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302 + H312 + H332-H319
Precautionary Statements P210-P280-P305 + P351 + P338
Hazard Codes T+
RIDADR UN 1648 3 / PGII
Flash Point(F) 35.6 °F
Flash Point(C) 2 °C

 Synonyms

13C15-Nivalenol
Trichothec-9-en-8-one-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-13C15, 12,13-epoxy-3,4,7,15-tetrahydroxy-, (2α,3α,4β,7α,12α)-
(3α,4β,7α)-3,4,7,15-Tetrahydroxy(2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-13C15)-12,13-epoxytrichothec-9-en-8-one
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