MAL3-101
Modify Date: 2024-02-21 13:47:02
MAL3-101 structure
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Common Name | MAL3-101 | ||
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| CAS Number | 912361-26-3 | Molecular Weight | 931.14 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C54H66N4O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MAL3-101MAL3-101 is a Hsc70 modulator that inhibits Hsp70 ATPase activity, exhibits antiproliferative activity in breast cancer cells SK-BR-3 with IC50 of 27 uM; also exhibits antimyeloma effects on MM cell lines in vitro and in vivo in a xenograft plasmacytoma model, as well as on primary tumor cells and bone marrow endothelial cells from myeloma patients. |
| Name | MAL3-101 |
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| Description | MAL3-101 is a Hsc70 modulator that inhibits Hsp70 ATPase activity, exhibits antiproliferative activity in breast cancer cells SK-BR-3 with IC50 of 27 uM; also exhibits antimyeloma effects on MM cell lines in vitro and in vivo in a xenograft plasmacytoma model, as well as on primary tumor cells and bone marrow endothelial cells from myeloma patients. |
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| References | References 1. Fewell SW, et al. J Biol Chem. 2004 Dec 3;279(49):51131-40. 2. Huryn DM, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6757-62. 3. Braunstein MJ, et al. J Oncol. 2011;2011:232037. doi: 10.1155/2011/232037. View Related Products by Target Heat Shock Protein (HSP) |
| Molecular Formula | C54H66N4O10 |
|---|---|
| Molecular Weight | 931.14 |