λ-Cyhalothrin

Modify Date: 2025-08-22 23:20:28

λ-Cyhalothrin structure	Common Name	λ-Cyhalothrin
	CAS Number	91465-08-6	Molecular Weight	899.700
	Density	1.33	Boiling Point	187-190°C
	Molecular Formula	C₂₃H₁₉ClF₃NO₃	Melting Point	49.2°C
	MSDS	Chinese USA	Flash Point	255.5ºC
	Symbol	GHS06, GHS09	Signal Word	Danger

Use of λ-Cyhalothrin

λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system[1].

Name	lambda-cyhalothrin
Synonym	More Synonyms

Description	λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Endocrinology Research Areas >> Infection Research Areas >> Neurological Disease
In Vitro	The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1]. λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1]. λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1]. λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1].
In Vivo	The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min[1].
References	[1]. Barbara Nieradko-Iwanicka, et al. Effect of Lambda-Cyhalothrin on Memory and Movement in Mice After Transient Incomplete Cerebral Ischemia. Ann Agric Environ Med. 2011;18(1):41-5.

Density	1.33
Boiling Point	187-190°C
Melting Point	49.2°C
Molecular Formula	C₂₃H₁₉ClF₃NO₃
Molecular Weight	899.700
Flash Point	255.5ºC
Exact Mass	898.201111
PSA	118.64000
LogP	13.08800
Index of Refraction	1.574
Storage condition	2-8°C

λ-Cyhalothrin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ1227780

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl- , cyano(3-phenoxyphenyl)methyl ester, (1-alpha(S*),3-alpha(Z))- (+-)-

CAS REGISTRY NUMBER :: 91465-08-6

LAST UPDATED :: 199610

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C23-H19-Cl-F3-N-O3

MOLECULAR WEIGHT :: 449.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,203,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 632 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,203,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1951 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 30,79,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >3950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C175,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 60 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,203,1991

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301 + H311-H330-H410
Precautionary Statements	Missing Phrase - N15.00950417-P260-P280-P302 + P352 + P312-P304 + P340 + P310-P403 + P233
Hazard Codes	T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases	R21;R25;R26;R50/53
Safety Phrases	1/2-28-36/37/39-38-45-60-61-13
RIDADR	UN 2810 6.1/PG 3
RTECS	GZ1227780
Packaging Group	I; II; III
Hazard Class	6.1

LAMOH-CYHALOTHRIN

lambda-Cyhalotrin

(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-rel-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate

LAMBDA CYHALOTHRIN

CYHALOTHRIN LAMBDA

α-cyano-3-phenoxybenzyl-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopropanecarboxylate

λ-Cyhalothrin

(Z)-cyano(3-phenoxyphenyl)methyl 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylate

Cyhalothrin-Lambda(Cyhalothrin)

(R)-Cyano(3-phenoxyphenyl)methyl (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate - (S)-cyano(3-phenoxyphenyl)methyl (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate (1:1)

rac-(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate

MFCD02181175

lambda-Cyhalothrin

of (R)-α-cyano-3-phenoxybenzyl (1S)-cis-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate and (S)-α-cyano-3-phenoxybenzyl (1R)-cis-3-[(Z)-2-chloro-3,3,3-trifluoropropenyl]-2,2-dimethylcyclopropanecarboxylate

EINECS 415-130-7

Cyhalothrin

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: λ-Cyhalothrin
Price: Check
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: λ-Cyhalothrin
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China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: lambda-Cyhalothrin
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: lambda-cyhalothrin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: λ-Cyhalothrin
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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λ-Cyhalothrin

Use of λ-Cyhalothrin

Names

λ-Cyhalothrin Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synonyms

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