demeton-S-methyl

Modify Date: 2025-09-07 03:42:23

demeton-S-methyl Structure
demeton-S-methyl structure
Common Name demeton-S-methyl
CAS Number 919-86-8 Molecular Weight 230.28500
Density 1.197g/cm3 Boiling Point 287.4ºC at 760 mmHg
Molecular Formula C6H15O3PS2 Melting Point <25℃
MSDS USA Flash Point 2ºC
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Names

Name demeton-S-methyl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.197g/cm3
Boiling Point 287.4ºC at 760 mmHg
Melting Point <25℃
Molecular Formula C6H15O3PS2
Molecular Weight 230.28500
Flash Point 2ºC
Exact Mass 230.02000
PSA 95.94000
LogP 2.87360
Index of Refraction 1.496

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TG1750000
CHEMICAL NAME :
Phosphorothioic acid, S-(2-(ethylthio)ethyl) O,O-dimethyl ester
CAS REGISTRY NUMBER :
919-86-8
BEILSTEIN REFERENCE NO. :
1707311
LAST UPDATED :
199703
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C6-H15-O3-P-S2
MOLECULAR WEIGHT :
230.30
WISWESSER LINE NOTATION :
2S2SPO&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
65 mg/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
12500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
80 ppm
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975 *** REVIEWS *** TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301 + H311-H411
Precautionary Statements P273-P280-P301 + P310 + P330-P302 + P352 + P312-P391-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T,N,Xn,F
Risk Phrases 24/25-51/53-36-20/21/22-11
Safety Phrases S26;S36/S37
RIDADR UN 3018
RTECS TG1750000
Packaging Group II
Hazard Class 6.1(a)

 Synthetic Route

~13%

demeton-S-methyl Structure

demeton-S-methyl

CAS#:919-86-8

Literature: Terreni, Marco; Pregnolato, Massimo; Resnati, Giuseppe; Benfenati, Emilio Tetrahedron, 1995 , vol. 51, # 29 p. 7981 - 7992

~%

demeton-S-methyl Structure

demeton-S-methyl

CAS#:919-86-8

Literature: DE947367 , ;

~%

demeton-S-methyl Structure

demeton-S-methyl

CAS#:919-86-8

Literature: Biochemical Journal, , vol. 67, p. 187,189,191 Journal of the Chemical Society, , p. 1643,1647,1649

~%

demeton-S-methyl Structure

demeton-S-methyl

CAS#:919-86-8

Literature: Zeitschrift fuer Naturforschung, , vol. 10b, p. 12,15-19

~%

demeton-S-methyl Structure

demeton-S-methyl

CAS#:919-86-8

Literature: Zeitschrift fuer Naturforschung, , vol. 10b, p. 12,15-19

 Articles25

More Articles
Mutagenesis of organophosphorus hydrolase to enhance hydrolysis of the nerve agent VX.

Biochem. Biophys. Res. Commun. 279(2) , 516-9, (2000)

Organophosphorus hydrolase (OPH) is capable of hydrolyzing a wide variety of organophosphorus pesticides and chemical warfare agents. However, the hydrolytic activity of OPH against the warfare agent ...

[First drafts of the Environmental Health Criteria (EHC) circulated for comments by IPCS in 1995-1996].

Eisei Shikenjo Hokoku. (114) , 95-8, (1996)

Genes coding for cytochrome P450 are regulated by endogenous hormones such as the growth hormone, corticosteroids, thyroid, and sex hormones. Secretion of these hormones is regulated by the respective...

[The decrement-increment phenomenon in disorders of neuromuscular transmission by inhibition of acetylcholinesterase].

EEG EMG Z. Elektroenzephalogr. Elektromyogr. Verwandte Geb. 20(1) , 28-33, (1989)

Repetitive stimulation of the median nerve elicited a so far unknown course of the muscle action potentials in four patients with organophosphate intoxications. The amplitude of the initial muscle act...

 Synonyms

Methyl isosystox
S-[2-(ethylsulfanyl)ethyl] O,O-dimethyl phosphorothioate
Metaisosystox
DEMETON-S-METHYL
S-2-ethylthioethyl O,O-dimethyl phosphorothioate
MFCD00055464
Thiometon oxon
Demetox
Metasystox J
O,O-dimethyl S-2-ethylthioethyl phosphorothioate
methylmercaptophos thiol
Metasystox 55
1-dimethoxyphosphorylsulfanyl-2-ethylsulfanylethane
EINECS 213-052-6
Metaisoseptox
S-[2-(ethylthio)ethyl] O,O-dimethyl phosphorothioate
Duratox
Methyldemetone
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.