Methacryloyl chloride

Modify Date: 2026-06-29 18:49:43

Methacryloyl chloride Structure
Methacryloyl chloride structure
Common Name Methacryloyl chloride
CAS Number 920-46-7 Molecular Weight 104.535
Density 1.1±0.1 g/cm3 Boiling Point 96.0±0.0 °C at 760 mmHg
Molecular Formula C4H5ClO Melting Point -60°C
MSDS Chinese USA Flash Point 27.7±11.9 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Methacryloyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 96.0±0.0 °C at 760 mmHg
Melting Point -60°C
Molecular Formula C4H5ClO
Molecular Weight 104.535
Flash Point 27.7±11.9 °C
Exact Mass 104.002892
PSA 17.07000
LogP 1.61
Vapour Pressure 44.4±0.1 mmHg at 25°C
Index of Refraction 1.425
InChIKey VHRYZQNGTZXDNX-UHFFFAOYSA-N
SMILES C=C(C)C(=O)Cl
Storage condition 2-8°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OZ5791000
CHEMICAL NAME :
Methacryloyl chloride
CAS REGISTRY NUMBER :
920-46-7
BEILSTEIN REFERENCE NO. :
0878175
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H5-Cl-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,80,1982
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
115 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,80,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.3 mg/m3;Skin JAN 1993

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger
Hazard Statements H225-H302-H314-H317-H330-H413
Precautionary Statements P210-P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F:Flammable;T+:Verytoxic;
Risk Phrases R11;R22;R26;R34
Safety Phrases S26-S28-S36/37/39-S45-S27-S16-S33-S29
RIDADR UN 3383 6.1/PG 1
WGK Germany 3
RTECS OZ5791000
Packaging Group I
Hazard Class 6.1

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~99%

Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: 3M INNOVATIVE PROPERTIES COMPANY Patent: WO2009/5937 A1, 2009 ; Location in patent: Page/Page column 30; 31 ;

~72%

Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: Xu, Zhifeng; Kuang, Daizhi; Feng, Yonglan; Zhang, Fuxing Carbohydrate Polymers, 2010 , vol. 79, # 3 p. 642 - 647

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Methacryloyl chloride Structure

Methacryloyl ch...

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Literature: US2490386 , ;

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Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: US2396609 , ;

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Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 787,797

~%

Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: Doklady Chemistry, , vol. 439, # 2 p. 219 - 222

~%

Methacryloyl chloride Structure

Methacryloyl ch...

CAS#:920-46-7

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Literature: Bulletin de la Societe Chimique de France, , p. 56

 Articles28

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Carbohydrate-Specific Uptake of Fucosylated Polymeric Micelles by Different Cancer Cell Lines.

Biomacromolecules 16 , 1948-57, (2015)

Inspired by upregulated levels of fucosylated proteins on the surfaces of multiple types of cancer cells, micelles carrying β-l-fucose and β-d-glucose were prepared. A range of block copolymers were s...

Effects of heating temperature and duration by gold nanorod mediated plasmonic photothermal therapy on copolymer accumulation in tumor tissue.

Mol. Pharm. 12 , 1605-14, (2015)

Previously, water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been used with gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) to induce hyperthermia (43 °C for 10...

Cholesterol-based polymeric monolithic columns for capillary liquid chromatography.

J. Chromatogr. A. 1373 , 114-23, (2014)

A novel, cholesterol-based polymeric monolithic stationary phase for capillary liquid chromatography, was prepared by thermally initiated in-situ polymerization. Cholesteryl methacrylate (CholMA) was ...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-Methylpropenal tosylhydrazone
MFCD00000716
methacrylic acid chloride
2-Methylprop-2-enoylchlorid
methacrolein toluene-4-sulphonylhydrazone
EINECS 213-058-9
2-methylpropenoic acid chloride
Methacryloyl chloride
2-Methylacryloyl chloride
2-methyl-acryloyl chloride
2-methyl-2-propenoyl chloride

 Methacryloyl chloride | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of Methacryloyl chloride?
A: SMILES notation of Methacryloyl chloride is C=C(C)C(=O)Cl.
Q: What English synonyms does Methacryloyl chloride have?
A: English synonyms of Methacryloyl chloride: 2-Methylpropenal tosylhydrazone, MFCD00000716, methacrylic acid chloride, 2-Methylprop-2-enoylchlorid, methacrolein toluene-4-sulphonylhydrazone, EINECS 213-058-9, 2-methylpropenoic acid chloride, Methacryloyl chloride, 2-Methylacryloyl chloride, 2-methyl-acryloyl chloride, 2-methyl-2-propenoyl chloride.
Q: What are the downstream products of Methacryloyl chloride?
A: Related downstream products(CAS) of Methacryloyl chloride: 108501-85-5;108871-76-7;106089-24-1;4655-34-9;3934-23-4;3253-41-6;585-07-9;355-93-1;352-87-4;3253-39-2.
Q: What is the molecular weight of Methacryloyl chloride?
A: Molecular weight of Methacryloyl chloride is 104.535.
Q: What is the LogP of Methacryloyl chloride?
A: LogP of Methacryloyl chloride is 1.61.
Q: What is the melting point of Methacryloyl chloride?
A: Melting point of Methacryloyl chloride is -60°C.
Q: What is the InChIKey of Methacryloyl chloride?
A: InChIKey of Methacryloyl chloride is VHRYZQNGTZXDNX-UHFFFAOYSA-N.
Q: What are the storage conditions for Methacryloyl chloride?
A: Storage conditions for Methacryloyl chloride: 2-8°C.
Q: What is the CAS number of Methacryloyl chloride?
A: CAS number of Methacryloyl chloride is 920-46-7.
Q: What is the boiling point of Methacryloyl chloride?
A: Boiling point of Methacryloyl chloride is 96.0±0.0 °C at 760 mmHg.

 Methacryloyl chloridefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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