Iodixanol

Modify Date: 2025-08-22 18:55:21

Iodixanol structure	Common Name	Iodixanol
	CAS Number	92339-11-2	Molecular Weight	1550.182
	Density	2.3±0.1 g/cm3	Boiling Point	1250.9±65.0 °C at 760 mmHg
	Molecular Formula	C₃₅H₄₄I₆N₆O₁₅	Melting Point	262-267ºC (dec.)
	MSDS	N/A	Flash Point	710.3±34.3 °C

Use of Iodixanol

Iodixanol is an iodine-containing non-ionic radiocontrast agent[1].

Name	iodixanol
Synonym	More Synonyms

Description	Iodixanol is an iodine-containing non-ionic radiocontrast agent[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vivo	Iodixanol exhibits less kidney toxicity[1].
References	[1]. Iodixanol.

Density	2.3±0.1 g/cm3
Boiling Point	1250.9±65.0 °C at 760 mmHg
Melting Point	262-267ºC (dec.)
Molecular Formula	C₃₅H₄₄I₆N₆O₁₅
Molecular Weight	1550.182
Flash Point	710.3±34.3 °C
Exact Mass	1549.713257
PSA	339.09000
LogP	-5.88
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.752
Storage condition	Refrigerator
Water Solubility	Freely soluble in water, sparingly soluble in methanol, practically insoluble in methylene chloride.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ3075000

CHEMICAL NAME :: 1,3-Benzenedicarboxamide, 5,5'-((2-hydroxy-1,3-propanediyl)bis(acetylimino))bis (N,N'- bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

CAS REGISTRY NUMBER :: 92339-11-2

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >42757 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - hemorrhage

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30512 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 73228 mg/kg/3W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 54921 mg/kg/3W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995

RIDADR	NONH for all modes of transport
HS Code	2924299090

2-(1,3-dichloro...

CAS#:28659-12-3

Iohexol Intermediate

CAS#:31127-80-7

Iodixanol

CAS#:92339-11-2

Literature: US7696381 B1, ; Page/Page column 4 ;

Iohexol Intermediate

CAS#:31127-80-7

Epichlorohydrin

CAS#:106-89-8

~68%

Iodixanol

CAS#:92339-11-2

Literature: HOVIONE CHINA HOLDING LIMITED; HU, Zhiqi; ZHANG, Huoying Patent: WO2011/63551 A1, 2011 ; Location in patent: Page/Page column 18 ;

Iohexol Intermediate

CAS#:31127-80-7

Epichlorohydrin

CAS#:106-89-8

~84%

Iohexol

CAS#:66108-95-0

Iodixanol

CAS#:92339-11-2

Literature: WO2011/63551 A1, ; Page/Page column 15-16 ;

1,3-Dichloro-2-...

CAS#:96-23-1

Iohexol Intermediate

CAS#:31127-80-7

Iodixanol

CAS#:92339-11-2

Literature: US7696381 B1, ; Page/Page column 4 ;

Iohexol Intermediate

CAS#:31127-80-7

Iohexol

CAS#:66108-95-0

Iodixanol

CAS#:92339-11-2

Literature: US2011/21829 A1, ; Page/Page column 5 ;

Precursor 4
CAS#:28659-12-3 2-(1,3-dichloro... CAS#:31127-80-7 Iohexol Intermediate CAS#:106-89-8 Epichlorohydrin CAS#:96-23-1 1,3-Dichloro-2-...
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Inhibition of CD40-induced N-Ras activation reduces leishmania major infection.

J. Immunol. 194(8) , 3852-60, (2015)

Leishmania major is a parasite that resides and replicates in macrophages. We previously showed that the parasite enhanced CD40-induced Raf-MEK-ERK signaling but inhibited PI3K-MKK-p38MAPK signaling t...

CD40 is required for protective immunity against liver stage Plasmodium infection.

J. Immunol. 194(5) , 2268-79, (2015)

The costimulatory molecule CD40 enhances immunity through several distinct roles in T cell activation and T cell interaction with other immune cells. In a mouse model of immunity to liver stage Plasmo...

Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells.

FASEB J. 28(12) , 5122-35, (2014)

Lon is a nuclear-encoded, mitochondrial protease that assists protein folding, degrades oxidized/damaged proteins, and participates in maintaining mtDNA levels. Here we show that Lon is up-regulated i...

1,3-Benzenedicarboxamide, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

5,5'-[(2-Hydroxypropane-1,3-diyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]

Q1YQ1MVR BI DI FI CVM1YQ1Q ENV1&1YQ1NV1&R BI DI FI CVM1YQ1Q EVM1YQ1Q

1,3-bis(acetylamino)-N,N'-bis[3,5-bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane

Iodixanolum [Latin]

Visipaque

Indixanol

3,3',5,5'-tetrakis(2,3-dihydroxypropylcarbamoyl)-2,2',4,4',6,6'-hexaiodo-N,N'-(2-hydroxypropane-1,3-diyl)diacetanilide

visipaqueTM

1,3-Benzenedicarboxamide, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

5-[acetyl-[3-[N-acetyl-3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodoanilino]-2-hydroxypropyl]amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

Iodixanolum

Visipaque 270

3,3',5',5'-tetrakis(2,3-dixydroxypropylcarbamoyl)-2,2',4,4',6,6'-hexaiodo-N,N'-(2-hydroxypropane-1,3-diyl)diacetanilide

UNII-HW8W27HTXX

5,5'-[(2-Hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]

Iodixanol

Visipaque 320

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Iodixanol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Iodixanol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Iodixanol
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: iodixanol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Iodixanol
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Iodixanol suppliers

Price: ￥1100/10 mM * 1 mL in DMSO

Reference only. check more Iodixanol price

Iodixanol

Use of Iodixanol

Names

Iodixanol Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles104

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.