VU534

Modify Date: 2025-11-26 21:20:32

VU534 Structure
VU534 structure
Common Name VU534
CAS Number 923509-20-0 Molecular Weight 447.55
Density N/A Boiling Point N/A
Molecular Formula C21H22FN3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VU534


VU534 is a NAPE-PLD activator, with an EC50 of 0.30 μM. VU534 is dual inhibitors of FAAH and sEH (IC50 of 1.2 μM). VU534 increases efferocytosis in a NAPE-PLD dependent manner. VU534 has the potential for cardiometabolic diseases study [1] .

 Names

Name VU534

 VU534 Biological Activity

Description VU534 is a NAPE-PLD activator, with an EC50 of 0.30 μM. VU534 is dual inhibitors of FAAH and sEH (IC50 of 1.2 μM). VU534 increases efferocytosis in a NAPE-PLD dependent manner. VU534 has the potential for cardiometabolic diseases study [1] .
Related Catalog
Target

NAPE-PLD activator, with an EC50 of 0.30 μM

References

[1]. Jonah E Zarrow, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem. Biol. 2023, 18, 8, 1891–1904.  

 Chemical & Physical Properties

Molecular Formula C21H22FN3O3S2
Molecular Weight 447.55
InChIKey RLHUIVPGYWWIQZ-UHFFFAOYSA-N
SMILES Cc1cc(C)c2sc(NC(=O)C3CCN(S(=O)(=O)c4ccc(F)cc4)CC3)nc2c1
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