FPND structure
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Common Name | FPND | ||
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CAS Number | 924866-33-1 | Molecular Weight | 429.493 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 680.3±65.0 °C at 760 mmHg | |
Molecular Formula | C24H24FN7 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 365.2±34.3 °C |
Use of FPNDA novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2; prevents atorvastatin-induced cerebral hemorrhage in zebrafish embryos (IC50=17.49 uM), by enhancing endothelial cell-cell junctions through inhibiting the ROCK-mediated VE-cadherin signaling pathway. |
Name | FPMINT |
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Synonym | More Synonyms |
Description | A novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2; prevents atorvastatin-induced cerebral hemorrhage in zebrafish embryos (IC50=17.49 uM), by enhancing endothelial cell-cell junctions through inhibiting the ROCK-mediated VE-cadherin signaling pathway. |
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References | References 1. Li S, et al. Cell Death Discov. 2017 Aug 21;3:17051. View Related Products by Target ROCK |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 680.3±65.0 °C at 760 mmHg |
Molecular Formula | C24H24FN7 |
Molecular Weight | 429.493 |
Flash Point | 365.2±34.3 °C |
Exact Mass | 429.207733 |
LogP | 3.57 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.717 |
6-{[4-(2-Fluorophenyl)-1-piperazinyl]methyl}-N-(1-naphthyl)-1,3,5-triazine-2,4-diamine |
6-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-N2-1-naphthalenyl-1,3,5-triazine-2,4-diamine |
FPMINT |
6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-N-(1-naphthyl)-1,3,5-triazine-2,4-diamine |
1,3,5-Triazine-2,4-diamine, 6-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-N2-1-naphthalenyl- |
4-((4-(2-Fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-1-yl)-1,3,5-triazin-2-amine |