Iohexol-d5

Modify Date: 2024-01-02 10:19:47

Iohexol-d5 Structure
Iohexol-d5 structure
Common Name Iohexol-d5
CAS Number 928623-33-0 Molecular Weight 826.17
Density N/A Boiling Point N/A
Molecular Formula C19H21D5I3N3O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Iohexol-d5


Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].

 Names

Name 5-[acetyl-(1,1,2,3,3-pentadeuterio-2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

 Iohexol-d5 Biological Activity

Description Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. James F Hainfeld, et al. Small, Long Blood Half-Life Iodine Nanoparticle for Vascular and Tumor Imaging. Sci Rep

 Chemical & Physical Properties

Molecular Formula C19H21D5I3N3O9
Molecular Weight 826.17
Exact Mass 825.91200
PSA 206.87000