5-HT3 antagonist 4

Modify Date: 2025-08-27 17:14:07

5-HT3 antagonist 4 structure	Common Name	5-HT3 antagonist 4
	CAS Number	930478-88-9	Molecular Weight	297.74
	Density	1.4±0.1 g/cm3	Boiling Point	388.9±42.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₂ClN₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	189.0±27.9 °C

Use of 5-HT3 antagonist 4

5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive phenotypes in mice[1].

Name	N-(3-Chloro-2-methylphenyl)-2-quinoxalinecarboxamide
Synonym	More Synonyms

Description	5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive phenotypes in mice[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Deepali Gupta, et al. A novel 5HT3 antagonist 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system. Behav Brain Res. 2016 Jan 15;297:41-50.

Density	1.4±0.1 g/cm3
Boiling Point	388.9±42.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₂ClN₃O
Molecular Weight	297.74
Flash Point	189.0±27.9 °C
Exact Mass	297.066895
LogP	4.12
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.707
InChIKey	SCIBFCFFUQXLCN-UHFFFAOYSA-N
SMILES	Cc1c(Cl)cccc1NC(=O)c1cnc2ccccc2n1

Name: Antidepressant-like activity in mouse assessed as immobility time at 2 mg/kg, ip by f...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273756

Name: Toxicity in mouse assessed as induction of spontaneous locomotor activity at 1 mg/kg,...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273757

Name: Toxicity in mouse assessed as induction of spontaneous locomotor activity at 0.5 mg/k...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273758

Name: Toxicity in mouse assessed as induction of spontaneous locomotor activity at 2 mg/kg,...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273759

Name: Antagonist activity 5-HT3A receptor in guinea pig ileum assessed as inhibition of 2-m...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 3A
External Id: CHEMBL4219564

Name: Antagonist activity at 5HT3 receptor in guinea pig ileum longitudinal muscle myenteri...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 3A
External Id: CHEMBL1273753

Name: Antidepressant-like activity in mouse assessed as immobility time at 1 mg/kg, ip by f...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273754

Name: Antidepressant-like activity in mouse assessed as immobility time at 0.5 mg/kg, ip by...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1273755

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N-(3-Chloro-2-methylphenyl)-2-quinoxalinecarboxamide

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5-HT3 antagonist 4

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.