p53 and MDM2 proteins-interaction-inhibitor (racemic)

Modify Date: 2024-01-07 21:50:07

p53 and MDM2 proteins-interaction-inhibitor (racemic) structure	Common Name	p53 and MDM2 proteins-interaction-inhibitor (racemic)
	CAS Number	939983-14-9	Molecular Weight	734.75400
	Density	1.24	Boiling Point	N/A
	Molecular Formula	C₄₀H₄₉Cl₂N₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of p53 and MDM2 proteins-interaction-inhibitor (racemic)

p53 and MDM2 proteins-interaction-inhibitor (racemic) (Compound 2j) is an inhibitor of the interaction between p53 and MDM2 proteins.

Name	2-[4-[(4R,5S)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazole-1-carbonyl]piperazin-1-yl]-1-morpholin-4-ylethanone
Synonym	More Synonyms

Description	p53 and MDM2 proteins-interaction-inhibitor (racemic) (Compound 2j) is an inhibitor of the interaction between p53 and MDM2 proteins.
Related Catalog	Signaling Pathways >> Apoptosis >> MDM-2/p53 Research Areas >> Cancer
References	[1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013 Apr 2;4(5):466-9.

Density	1.24
Molecular Formula	C₄₀H₄₉Cl₂N₅O₄
Molecular Weight	734.75400
Exact Mass	733.31600
PSA	77.92000
LogP	6.36620
Storage condition	2-8℃

2-(4-((4R,5S)-2-(4-(tert-Butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-1-yl)-1-morpholinoethanone

p53 and MDM2 proteins-interaction-inhibitor racemic

p53 and MDM2 proteins-interaction-inhibitor (racemic)

p53 and MDM2 proteins-interaction-inhibitor (racemic)

Use of p53 and MDM2 proteins-interaction-inhibitor (racemic)

Names

Biological Activity

Chemical & Physical Properties

Synonyms